Date published: 2026-4-4

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CaMK Substrates

Santa Cruz Biotechnology now offers a broad range of CaMK Substrates for use in various applications. CaMK substrates are essential tools in the study of calcium/calmodulin-dependent protein kinases (CaMKs), which play a critical role in translating calcium signals into cellular responses. These substrates are typically proteins or peptides that are specifically phosphorylated by CaMKs, making them indispensable for investigating the activity and specificity of these kinases in different biological contexts. The use of CaMK substrates allows researchers to explore the mechanisms by which CaMKs regulate a variety of cellular processes, including gene expression, synaptic plasticity, and muscle contraction. By analyzing the phosphorylation patterns of these substrates, scientists can gain insights into the pathways controlled by CaMKs and their role in cellular signaling networks. CaMK substrates are widely used in assays to measure kinase activity, enabling the detailed study of how CaMKs are activated and how they, in turn, modify their target proteins. These substrates also serve as valuable tools in high-throughput screening applications, where they help identify potential modulators of CaMK activity. The ability to work with specific CaMK substrates provides researchers with a deeper understanding of how calcium signaling is integrated into broader cellular functions and how it influences processes such as learning, memory, and cell cycle regulation. The use of CaMK substrates in research not only advances our knowledge of kinase-substrate interactions but also contributes to the development of new experimental approaches to study signal transduction. View detailed information on our available CaMK Substrates by clicking on the product name.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

syntide-2 substrate

sc-3015
0.5 mg/0.1 ml
$96.00
15
(0)

Syntide-2 substrate serves as a selective activator of calcium/calmodulin-dependent protein kinases (CaMKs) by engaging in precise hydrogen bonding and hydrophobic interactions with critical amino acid residues. This substrate's unique conformation stabilizes the enzyme-substrate complex, leading to enhanced catalytic efficiency. Its distinct molecular architecture allows for specific pathway modulation, impacting the dynamics of cellular signaling cascades and influencing various physiological processes.

CaM Kinase IV substrate

sc-3028
0.5 mg/0.1 ml
$96.00
(0)

CaM Kinase IV substrate is a pivotal component in calcium/calmodulin-dependent signaling pathways, characterized by its ability to undergo conformational changes upon calcium binding. This substrate exhibits a high affinity for the kinase, facilitating rapid phosphorylation events. Its unique sequence promotes specific interactions with the enzyme's active site, enhancing substrate recognition and specificity. The substrate's dynamic behavior influences downstream signaling, contributing to the regulation of various cellular functions.

casein kinase I substrate Substrate

154444-97-0sc-3120
0.5 mg
$96.00
(0)

Casein kinase I substrate plays a crucial role in cellular signaling by participating in phosphorylation processes that modulate protein interactions and stability. Its unique structural motifs allow for selective binding to casein kinase I, promoting efficient substrate recognition. The substrate's phosphorylation kinetics are influenced by its conformational flexibility, which enables it to adapt to different cellular environments. This adaptability is essential for fine-tuning various signaling pathways and cellular responses.