Calcium Channel Modulators
Items 51 to 60 of 167 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ziconotide Polyacetate | sc-213176 | 0.25 mg | $605.00 | |||
Ziconotide Polyacetate acts as a calcium channel modulator through its ability to bind to and stabilize specific conformations of calcium channels. Its unique polyacetate structure enhances hydrophilicity, facilitating interactions with channel proteins. This compound exhibits selective inhibition of calcium ion flow, impacting cellular excitability and neurotransmitter release. The intricate balance of its molecular interactions and kinetic properties underscores its role in modulating calcium-dependent physiological processes. | ||||||
Proadifen hydrochloride | 62-68-0 | sc-200492 sc-200492A | 250 mg 1 g | $144.00 $421.00 | 1 | |
Proadifen hydrochloride functions as a calcium channel modulator by selectively interacting with voltage-gated calcium channels, altering their conformational states. Its unique structure promotes specific binding affinities, influencing ion permeability and channel kinetics. This compound exhibits a distinct mechanism of action, characterized by its ability to fine-tune calcium ion influx, thereby affecting cellular signaling pathways and excitability. The nuanced interplay of its molecular interactions highlights its role in calcium homeostasis. | ||||||
FPL-64176 | 120934-96-5 | sc-201491 | 5 mg | $83.00 | 1 | |
FPL-64176 acts as a calcium channel modulator through its selective binding to specific sites on voltage-gated calcium channels, leading to alterations in channel dynamics. Its unique molecular architecture facilitates distinct interactions that enhance or inhibit calcium ion flow, impacting the activation thresholds and inactivation rates of these channels. This compound showcases a remarkable ability to influence calcium-dependent processes, underscoring its intricate role in cellular calcium regulation. | ||||||
SK&F 96365 | 130495-35-1 | sc-201475 sc-201475B sc-201475A sc-201475C | 5 mg 10 mg 25 mg 50 mg | $103.00 $158.00 $397.00 $656.00 | 2 | |
SK&F 96365 functions as a calcium channel modulator by selectively interacting with intracellular signaling pathways that regulate calcium influx. Its unique structural features allow it to disrupt the normal gating mechanisms of calcium channels, leading to altered ion permeability. This compound exhibits a distinctive kinetic profile, influencing the rate of calcium ion entry and contributing to the modulation of cellular excitability and signaling cascades. | ||||||
CAY10502 | 888320-29-4 | sc-223866 sc-223866A sc-223866B sc-223866C | 500 µg 1 mg 5 mg 10 mg | $44.00 $81.00 $337.00 $591.00 | ||
CAY10502 acts as a calcium channel modulator by engaging with specific binding sites on calcium channels, altering their conformational states. This compound exhibits a unique ability to stabilize intermediate states of the channel, thereby influencing ion flow dynamics. Its interaction with lipid bilayers enhances membrane fluidity, which can further impact channel activity. The compound's distinct molecular architecture allows for selective modulation of calcium-dependent processes, showcasing its intricate role in cellular signaling. | ||||||
Metastin | sc-221884 | 500 µg | $310.00 | |||
Metastin functions as a calcium channel modulator by selectively interacting with the voltage-sensing domains of calcium channels, leading to altered gating kinetics. This compound exhibits a unique capacity to enhance the channel's responsiveness to membrane potential changes, thereby fine-tuning calcium influx. Its structural features promote specific interactions with surrounding lipid environments, potentially affecting channel localization and clustering within the membrane, which can further influence cellular excitability and signaling pathways. | ||||||
6-Benzylaminopurine | 1214-39-7 | sc-202428 sc-202428A | 1 g 5 g | $20.00 $52.00 | ||
6-Benzylaminopurine acts as a calcium channel modulator by engaging with specific binding sites on calcium channels, influencing their conformational states. This compound alters the kinetics of calcium ion flow, enhancing or inhibiting channel activity based on the cellular context. Its unique aromatic structure allows for distinct interactions with lipid bilayers, potentially affecting membrane fluidity and the spatial organization of calcium channels, thereby modulating intracellular calcium dynamics. | ||||||
(R)-(-)-Niguldipine hydrochloride | 113145-70-3 | sc-203676 sc-203676A | 10 mg 50 mg | $185.00 $781.00 | ||
(R)-(-)-Niguldipine hydrochloride functions as a calcium channel modulator by selectively interacting with L-type calcium channels, stabilizing their open states and influencing ion permeability. Its stereochemistry contributes to its affinity for specific channel subtypes, leading to nuanced effects on calcium influx. The compound's hydrophobic regions facilitate interactions with membrane lipids, potentially altering channel localization and dynamics, which can impact cellular signaling pathways and calcium homeostasis. | ||||||
Lercanidipine hydrochloride hemihydrate | 132866-11-6 (anhydrous) | sc-252951 | 10 mg | $134.00 | ||
Lercanidipine hydrochloride hemihydrate acts as a calcium channel modulator by preferentially binding to L-type calcium channels, promoting a conformational change that enhances channel gating. Its unique structural features allow for specific interactions with channel proteins, influencing the kinetics of calcium ion flow. The compound's solubility characteristics and hydrophilic-lipophilic balance may affect its distribution within cellular membranes, thereby modulating cellular excitability and calcium signaling pathways. | ||||||
trans-Ned 19 | 1354235-96-3 | sc-362814 | 10 mg | $339.00 | 3 | |
Trans-Ned 19 functions as a calcium channel modulator by selectively interacting with voltage-gated calcium channels, stabilizing their inactive state and thereby reducing calcium influx. Its unique stereochemistry facilitates specific binding interactions that alter channel dynamics, impacting the rate of ion conduction. Additionally, the compound exhibits distinct lipophilic properties, influencing its membrane permeability and the modulation of intracellular calcium homeostasis, ultimately affecting cellular signaling cascades. | ||||||