Calcium Channel Modulators
Items 121 to 130 of 167 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MRS 1845 | 544478-19-5 | sc-203636 sc-203636A | 5 mg 50 mg | $213.00 $1248.00 | ||
MRS 1845 is a novel calcium channel modulator that exhibits unique binding affinity for specific channel subtypes, influencing ion permeability and cellular excitability. Its distinct molecular interactions facilitate the stabilization of channel conformations, altering the kinetics of calcium influx. This compound's ability to fine-tune calcium signaling pathways is attributed to its selective engagement with regulatory sites, providing insights into calcium homeostasis and cellular response mechanisms. | ||||||
Xestospongin D | sc-222422 | 50 µg | $522.00 | |||
Xestospongin D is a potent calcium channel modulator that selectively interacts with inositol trisphosphate receptors, disrupting calcium release from intracellular stores. Its unique mechanism involves altering the receptor's conformational dynamics, which impacts downstream signaling cascades. By modulating the sensitivity of these channels to ligands, Xestospongin D plays a critical role in regulating calcium-mediated processes, showcasing its distinct influence on cellular calcium dynamics. | ||||||
Kurtoxin | sc-300858 | 100 µg | $334.00 | |||
Kurtoxin is a specialized calcium channel modulator that exhibits a unique affinity for voltage-gated calcium channels, particularly influencing their gating kinetics. It alters the channel's activation threshold, leading to a nuanced modulation of calcium influx. This compound's distinct interaction with specific channel subtypes enhances its ability to fine-tune calcium signaling pathways, thereby affecting various cellular processes. Its selective binding properties contribute to its role in shaping calcium-dependent cellular responses. | ||||||
Thionicotinamide adenine dinucleotidephosphate potassium salt | sc-394300 | 100 mg | $837.00 | 1 | ||
Thionicotinamide adenine dinucleotidephosphate potassium salt serves as a calcium channel modulator by engaging in intricate molecular interactions that stabilize channel conformations. This compound influences calcium ion permeability through specific binding sites, thereby affecting the kinetics of channel opening and closing. Its unique structural features allow it to selectively target certain calcium channel subtypes, modulating intracellular calcium levels and impacting cellular excitability and signaling cascades. | ||||||
Somatostatin | 51110-01-1 | sc-391009 sc-391009A | 1 mg 5 mg | $114.00 $536.00 | 9 | |
Somatostatin functions as a calcium channel modulator by interacting with specific receptor sites on calcium channels, leading to altered channel dynamics. This peptide influences the gating mechanisms, effectively reducing calcium influx and modulating downstream signaling pathways. Its unique conformation allows for selective binding, impacting the kinetics of calcium release and contributing to the regulation of various physiological processes at the cellular level. | ||||||
Nemadipine-B | 79925-38-5 | sc-203157 | 10 mg | $281.00 | ||
Nemadipine-B acts as a calcium channel modulator by selectively binding to L-type calcium channels, altering their conformational states. This interaction enhances the channel's inactivation kinetics, leading to a decrease in calcium ion permeability. Its unique structural features facilitate specific molecular interactions that fine-tune the channel's response to voltage changes, thereby influencing calcium-dependent signaling cascades and cellular excitability. | ||||||
(S)-(-)-Felodipine | 105618-03-9 | sc-212833 | 1 mg | $380.00 | ||
(S)-(-)-Felodipine functions as a calcium channel modulator by preferentially interacting with L-type calcium channels, stabilizing their inactive state. This selective binding alters the channel's gating dynamics, resulting in a reduced influx of calcium ions. Its stereochemistry contributes to distinct molecular interactions that enhance the modulation of channel activity, impacting calcium homeostasis and influencing various cellular processes through altered signaling pathways. | ||||||
(R)-(+)-Felodipine | 119945-59-4 | sc-212658 | 1 mg | $380.00 | ||
(R)-(+)-Felodipine acts as a calcium channel modulator by selectively binding to L-type calcium channels, promoting a conformational shift that enhances channel inactivation. This stereoisomer exhibits unique kinetic properties, leading to a slower recovery from inactivation compared to its counterpart. The specific spatial arrangement of its functional groups facilitates unique interactions with channel residues, fine-tuning calcium ion flux and influencing downstream signaling cascades. | ||||||
Calcicludine II | 178037-96-2 | sc-293976 | 70 µg | $592.00 | ||
Calcicludine II functions as a calcium channel modulator by engaging with voltage-gated calcium channels, inducing a distinct allosteric modulation that alters channel gating dynamics. Its unique structural features allow for selective interaction with specific amino acid residues, resulting in a differential impact on ion permeability. This compound exhibits notable reaction kinetics, characterized by a rapid onset of action and prolonged effects, which are influenced by its hydrophobic regions that enhance membrane affinity. | ||||||
Lercanidipine-d3 (hydrochloride) | 187731-34-6 (unlabeled) | sc-221841 sc-221841A | 1 mg 5 mg | $304.00 $772.00 | ||
Lercanidipine-d3 (hydrochloride) acts as a calcium channel modulator by selectively binding to L-type calcium channels, leading to a unique conformational change that stabilizes the inactive state of the channel. This compound's isotopic labeling enhances its stability and tracking in biochemical assays. Its distinct hydrophilic and lipophilic balance facilitates effective membrane penetration, influencing its interaction kinetics and modulating calcium ion flux with precision. | ||||||