C20orf144 Activators

Chromosome 20 open reading frame 144, commonly abbreviated as C20orf144, is a protein that is encoded by the C20orf144 gene situated on the 20th chromosome in humans. As with many open reading frame (ORF) proteins, the specific biological functions of C20orf144 have not been thoroughly elucidated, which places it in the category of proteins that are not well-understood or characterized within the context of cellular mechanisms and pathways.

The term 'open reading frame' refers to a sequence of DNA that is predicted to encode a protein, and it is identified by the presence of a start codon followed by a sequence of codons that do not contain a stop codon until the appropriate termination signal is reached. The numbering '144' serves as an identifier to distinguish this ORF from others on chromosome 20, with 'C20' indicating its chromosomal position.The study of C20orf144, like other orphan proteins, often starts with in silico analyses that predict the protein's structure and potential domains based on its amino acid sequence. This computational approach can suggest possible functional roles by comparing it to known protein domains and motifs. However, experimental validation is required to confirm these hypotheses.