C20orf144 Inhibitors
Chromosome 20 open reading frame 144, commonly abbreviated as C20orf144, is a protein that, as suggested by its name, is encoded by a gene located on the 20th chromosome within a segment known as an open reading frame. Open reading frames (ORFs) are stretches of DNA sequences that have the potential to be translated into proteins. They are characterized by a start codon (usually ATG in DNA), which signals the beginning of protein synthesis, and a stop codon that terminates translation.
C20orf144 may be implicated in a variety of cellular functions depending on its structure and the domains it contains. It could be involved in cellular signaling, gene regulation, or other vital cellular operations. Proteins encoded by ORFs can also be specific to certain tissues or developmental stages, playing roles in growth, differentiation, or maintaining homeostasis.Research into C20orf144 involves understanding its expression pattern, post-translational modifications, interaction with other proteins, and involvement in any disease states. This is achieved through a range of techniques including but not limited to bioinformatics analyses, gene knockdown or knockout studies, protein expression profiling, and functional assays.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is a potent inhibitor of phosphoinositide 3-kinases (PI3K), which are involved in various cellular processes including growth, proliferation, and survival. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a selective inhibitor of PI3Ks, specifically targeting the ATP binding site of these enzymes, thereby inhibiting their activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin is an mTOR inhibitor, acting on the mTORC1 complex, which is crucial in regulating cell growth and protein synthesis. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a specific inhibitor of mitogen-activated protein kinase kinase (MEK), which is a part of the MAPK/ERK pathway involved in cell differentiation and proliferation. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is a non-competitive inhibitor of MEK1/2, effectively blocking the MAPK/ERK signaling pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a selective inhibitor of p38 MAPK, involved in inflammatory responses and stress-induced cellular pathways. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is an inhibitor of c-Jun N-terminal kinase (JNK), impacting processes like apoptosis, inflammation, and cellular differentiation. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Bortezomib is a proteasome inhibitor, affecting multiple signaling pathways due to the accumulation of undegraded proteins. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG132 is a peptide aldehyde that inhibits the proteasome, leading to cell cycle arrest and apoptosis. | ||||||
Z-VAD-FMK | 187389-52-2 | sc-3067 | 500 µg | $74.00 | 256 | |
Z-VAD-FMK is a pan-caspase inhibitor, which can indirectly affect apoptosis pathways, potentially influencing C20orf144-related processes. | ||||||