C1orf52_2410004B18Rik Inhibitors
C1orf52_2410004B18Rik Inhibitors are a diverse group of chemical compounds that exert their effects through various signaling pathways, leading to the inhibition of C1orf52_2410004B18Rik's functional role in cellular processes. Staurosporine and Bortezomib, as broad-spectrum kinase and proteasome inhibitors, respectively, may lead to decreased phosphorylation states and selective degradation of proteins, potentially diminishing the functional activity of C1orf52_2410004B18Rik, provided its activity is contingent upon these post-translational modifications. Similarly, LY 294002 and Rapamycin are specific to the PI3K/AKT/mTOR pathway and could suppress downstream effects that stabilize or activate C1orf52_2410004B18Rik, assuming it is implicated in these signaling cascades. The MEK inhibitors, PD 98059 and U0126, target the MAPK/ERK pathway, which, if linked to C1orf52_2410004B18Rik functionality, would lead to its decreased activity upon suppression of the pathway. In parallel, SB 203580's inhibition of p38 MAPK could yield a similar outcome if C1orf52_2410004B18Rik operates downstream of or is regulated by p38 MAPK activity.
The intricate cellular signaling network offers multiple targets for indirect inhibition of C1orf52_2410004B18Rik, with chemicals such as SP600125 and BML-275 targeting the JNK and AMPK/BMP pathways, respectively. Y-27632's inhibition of ROCK kinases would be relevant if C1orf52_2410004B18Rik is associated with actin cytoskeleton dynamics. ZM-447439 further expands the arsenal as an Aurora kinase inhibitor, diminishing C1orf52_2410004B18Rik's potential involvement in cell division processes. WZ8040 could also indirectly diminish C1orf52_2410004B18Rik activity through NUAK family kinase inhibition, which is implicated in energy homeostasis and stress responses. Each of these chemicals, through their targeted inhibition of specific pathways, could logically lead to the decreased functional activity of C1orf52_2410004B18Rik, thereby serving as effective indirect inhibitors.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
A potent, non-selective inhibitor of protein kinases. Inhibits many kinases that could phosphorylate C1orf52_2410004B18Rik, potentially reducing its functional activity if phosphorylation is required for its function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A selective inhibitor of PI3K. Inhibition of PI3K signaling would attenuate downstream AKT activation, which could be necessary for the stabilization and activity of C1orf52_2410004B18Rik. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
A selective inhibitor of MEK, which could diminish ERK pathway signaling. If C1orf52_2410004B18Rik activity is linked to the ERK pathway, this inhibition could reduce its activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor known to affect cell growth and proliferation. If C1orf52_2410004B18Rik is involved in these processes, mTOR inhibition could decrease its functional activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A specific inhibitor of p38 MAPK. If C1orf52_2410004B18Rik works downstream or is regulated by p38 MAPK, its inhibition could lead to decreased C1orf52_2410004B18Rik activity. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
A selective inhibitor of MEK1/2, preventing the activation of ERK1/2. If the activity of C1orf52_2410004B18Rik is modulated by the ERK pathway, this inhibitor would lead to its reduced function. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
A proteasome inhibitor that can lead to increased cellular stress and potentially downregulate proteins that are not essential for cell survival, possibly including C1orf52_2410004B18Rik. | ||||||
WZ8040 | 1214265-57-2 | sc-364656 sc-364656A | 5 mg 10 mg | $255.00 $480.00 | ||
An inhibitor of NUAK family kinase, which could play a role in energy homeostasis and stress responses. If C1orf52_2410004B18Rik is involved in these processes, inhibition could diminish its activity. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
An inhibitor of JNK, which modulates apoptosis and cell proliferation. If C1orf52_2410004B18Rik is involved in these pathways, JNK inhibition could indirectly decrease its activity. | ||||||
BML-275 | 866405-64-3 | sc-200689 sc-200689A | 5 mg 25 mg | $94.00 $348.00 | 69 | |
An inhibitor of AMPK and BMP signaling. If C1orf52_2410004B18Rik activity is associated with energy metabolism or BMP signaling pathways, this inhibitor could reduce its activity. | ||||||