C1orf114 Inhibitors
Coiled-coil domain-containing protein 181 Inhibitors would comprise chemical compounds that either directly or indirectly influence the expression, stability, or function of Coiled-coil domain-containing protein 181. Given the central role of this protein in binding to microtubules, especially in the context of spermatids, effective inhibitors in this class would be anticipated to interfere with such interactions, leading to potential disruptions in microtubule dynamics or related cellular processes.
The compounds that belong to this class would be expected to act at various levels of gene expression, from DNA transcription to protein translation and post-translational modifications. For example, some inhibitors might block the transcription of the gene encoding the Coiled-coil domain-containing protein 181, while others might prevent its proper folding or stability post-translation. Given the diversity of the potential modes of action and the specificity required to target just one protein, this class would likely encompass a broad range of molecular structures and mechanisms. Furthermore, understanding the detailed biochemistry and cell biology of Coiled-coil domain-containing protein 181 would be essential for developing and characterizing these inhibitors, ensuring specificity and minimizing off-target effects.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
This compound intercalates into DNA, potentially preventing transcription of genes, including Coiled-coil domain-containing protein 181. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Known to inhibit translation in eukaryotic cells which might decrease the production of Coiled-coil domain-containing protein 181. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
It gets incorporated into RNA, potentially disrupting the synthesis of proteins like Coiled-coil domain-containing protein 181. | ||||||
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
This compound crosslinks DNA, potentially disrupting the transcription of genes like Coiled-coil domain-containing protein 181. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
By inhibiting mTOR pathway, it could reduce translation of certain proteins, possibly including Coiled-coil domain-containing protein 181. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Known to block N-linked glycosylation and can affect proper folding and stability of some proteins. Might affect Coiled-coil domain-containing protein 181 if it requires such modifications. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Specifically inhibits RNA polymerase II, potentially preventing the transcription of genes like Coiled-coil domain-containing protein 181. | ||||||
Streptonigrin | 3930-19-6 | sc-500892 sc-500892A | 1 mg 5 mg | $102.00 $357.00 | 1 | |
This antibiotic interferes with RNA elongation, potentially affecting the synthesis of Coiled-coil domain-containing protein 181. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Inhibits DNA topoisomerase I which might affect DNA unwinding and subsequently genes like Coiled-coil domain-containing protein 181 transcription. | ||||||
Spliceostatin A | 391611-36-2 | sc-507481 | 1 mg | $1800.00 | ||
It targets the spliceosome, potentially affecting mRNA splicing and maturation of Coiled-coil domain-containing protein 181 transcripts. | ||||||