C19orf56 inhibitors are a class of chemical compounds that target various signaling pathways and enzymes to indirectly diminish the activity of C19orf56. For example, kinase inhibitors like staurosporine exert their effect by broadly inhibiting protein kinases, which are essential for phosphorylating proteins that may be necessary for the proper functioning of C19orf56. Inhibition of these kinases would prevent the phosphorylation and subsequent activation of proteins involved in the regulation of C19orf56 activity, thereby leading to its reducedfunctional activity.
Compounds such as LY294002 and wortmannin specifically inhibit the PI3K/AKT signaling pathway. This pathway is critical for numerous cellular functions, including survival, growth, and metabolism. Since it is plausible that C19orf56 functions downstream of or is regulated by PI3K/AKT signaling, the inhibition of this pathway by LY294002 and wortmannin would result in an indirect reduction of C19orf56 activity by preventing essential phosphorylation events or the activation of secondary messengers that modulate its activity. Similarly, the inhibition of mTOR by rapamycin could lead to decreased C19orf56 activity if C19orf56 is involved in pathways downstream of mTOR, such as protein synthesis or cell cycle progression.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Roscovitine | 186692-46-6 | sc-24002 sc-24002A | 1 mg 5 mg | $92.00 $260.00 | 42 | |
Roscovitine is a selective inhibitor of cyclin-dependent kinases (CDKs). If C19orf56 activity is CDK-dependent, then roscovitine’s inhibition of CDKs can lead to reduced C19orf56 activity. | ||||||
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | $46.00 $140.00 $680.00 | 16 | |
PD173074 is a selective inhibitor of the FGFR tyrosine kinase. If C19orf56 is functionally connected to FGFR signaling, inhibition by PD173074 could lead to a decrease in C19orf56 activity. | ||||||