The class of chemicals referred to as C11orf58_1110004F10Rik inhibitors primarily focus on broadly influencing cellular processes that can indirectly modulate the function or expression of C11orf58_1110004F10Rik. Given the current ambiguity around this protein's specific role, this approach relies on the principle that cellular proteins don't operate in isolation but are part of intricate networks.
For instance, inhibitors like Cycloheximide and MG132 can influence protein synthesis and degradation, respectively. By modulating these core processes, the levels and activity of a myriad of proteins, including C11orf58_1110004F10Rik, can be affected. On the signaling front, chemicals such as LY294002 and U0126 target PI3K and MEK1/2 pathways, respectively. These pathways play pivotal roles in various cellular processes, from growth and survival to differentiation. By inhibiting them, one can induce wide-reaching effects, which can indirectly impact the activity or levels of C11orf58_1110004F10Rik. Similarly, compounds like Wortmannin and Rapamycin exert their effects on PI3K and mTOR pathways, highlighting how the manipulation of central cellular signaling cascades can influence proteins, even if their specific roles remain undefined.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Inhibits protein synthesis, can reduce levels of most proteins in a cell. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
Proteasome inhibitor, prevents protein degradation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor, affects a broad range of cellular signaling pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Another PI3K inhibitor, impacts various cellular processes. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor, affecting protein synthesis and cellular growth processes. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
General kinase inhibitor, affecting a variety of cellular signaling pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK, a component of the MAPK pathway. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A sc-24000B sc-24000C | 10 µg 100 µg 500 µg 1 mg | $160.00 $750.00 $1400.00 $3000.00 | 59 | |
Protein phosphatase inhibitor, affecting protein phosphorylation status. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Disrupts protein transport from the endoplasmic reticulum. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $58.00 $83.00 $140.00 $242.00 | 38 | |
Disrupts microtubules, affecting cell division and transport processes. |