BRAK Activators
BRAK activators are a class of activators that can potentially influence the expression of the chemokine BRAK. These activators primarily function by modulating intracellular cAMP levels, which can impact chemokine expression. Members of this class increase cAMP levels by activating adenylate cyclase and inhibiting phosphodiesterases, respectively.
Additional members of this class are activators that interact with prostaglandin receptors. These activators can increase intracellular cAMP levels through activation of specific prostaglandin receptors, potentially leading to increased BRAK expression. Other members of this class are prostaglandin analogues which can potentially modulate BRAK expression through their actions on prostaglandin pathways.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin is a diterpene that activates adenylate cyclase, increasing cAMP levels. Elevated cAMP can influence chemokine expression, potentially leading to increased BRAK expression. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX is a nonspecific inhibitor of phosphodiesterases, leading to an increase in intracellular cAMP levels. This can lead to increased chemokine expression, including BRAK. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram is a selective inhibitor of phosphodiesterase 4, leading to an increase in cAMP levels. Elevated cAMP can lead to increased BRAK expression. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
PGE2 is a prostaglandin that activates the EP2 receptor, resulting in increased intracellular cAMP levels. This can potentially increase BRAK expression. | ||||||
Butaprost | 69685-22-9 | sc-221387 sc-221387A | 500 µg 1 mg | $126.00 $242.00 | 1 | |
Butaprost is a selective EP2 receptor agonist. Activation of the EP2 receptor leads to increased cAMP levels, which can potentially increase BRAK expression. | ||||||
Sulprostone | 60325-46-4 | sc-201348 sc-201348A | 1 mg 5 mg | $224.00 $774.00 | 8 | |
Sulprostone is a potent agonist for EP1 and EP3 receptors. Activation of these receptors can potentially lead to modulation of chemokine expression, including BRAK. | ||||||
PGE1 (Prostaglandin E1) | 745-65-3 | sc-201223 sc-201223A | 1 mg 10 mg | $31.00 $145.00 | 16 | |
PGE1 is a naturally occurring prostaglandin E1 (PGE1) that can increase cAMP levels. This can potentially lead to increased BRAK expression. | ||||||
Misoprostol | 59122-46-2 | sc-201264 sc-201264A sc-201264B | 10 mg 100 mg 1 g | $183.00 $1149.00 $7080.00 | 2 | |
Misoprostol is a synthetic PGE1 analogue that can increase cAMP levels, potentially leading to increased BRAK expression. | ||||||
Bimatoprost | 155206-00-1 | sc-205224 sc-205224A | 1 mg 5 mg | $120.00 $464.00 | 1 | |
Bimatoprost is a prostaglandin analogue that can potentially modulate chemokine expression, including BRAK. | ||||||