BPAG1 Inhibitors
BPAG1 inhibitors belong to a specialized class of chemical compounds designed to target a specific cellular protein known as BPAG1, or Bullous Pemphigoid Antigen 1. BPAG1 is a key component of the hemidesmosome, a specialized structure within epithelial cells that plays a crucial role in cell adhesion to the extracellular matrix. These inhibitors are meticulously crafted to modulate the function of BPAG1, impacting its interactions with other proteins or cellular processes without necessarily inducing any effects.
BPAG1 inhibitors can encompass a diverse range of compounds, including small molecules or biologics, each designed to interact with BPAG1 in distinct ways. These inhibitors can interfere with BPAG1's binding affinity to other proteins or molecules, disrupt its post-translational modifications, or even affect its cellular localization. Such interactions can have far-reaching consequences on cell adhesion, cytoskeletal dynamics, and tissue integrity, making BPAG1 inhibitors an essential tool in basic research to dissect the molecular mechanisms underpinning cell adhesion and migration.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Inhibits actin filament polymerization, potentially impacting actin interactions with BPAG1. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $72.00 $265.00 $495.00 $968.00 | ||
Inhibits myosin II, potentially affecting cellular processes that involve BPAG1. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Disrupts microtubule dynamics, could indirectly influence BPAG1's role in cellular structure. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
ROCK inhibitor, can affect actin cytoskeleton dynamics, indirectly impacting BPAG1. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Disrupts actin polymerization, potentially affecting BPAG1's interactions with actin. | ||||||
ML-7 hydrochloride | 110448-33-4 | sc-200557 sc-200557A | 10 mg 50 mg | $91.00 $267.00 | 13 | |
Inhibits myosin light chain kinase, could influence cytoskeletal interactions involving BPAG1. | ||||||
Jasplakinolide | 102396-24-7 | sc-202191 sc-202191A | 50 µg 100 µg | $184.00 $305.00 | 59 | |
Stabilizes actin filaments, potentially affecting actin-related functions of BPAG1. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Activates adenylate cyclase, potentially affecting signaling pathways related to BPAG1 function. | ||||||
Phalloidin | 17466-45-4 | sc-202763 | 1 mg | $234.00 | 33 | |
Stabilizes actin filaments, could affect actin cytoskeleton dynamics involving BPAG1. | ||||||