BLP2 Activators
BLP2 Activators comprise a group of chemical compounds that indirectly facilitate the functional activity of BLP2, predominantly through their interactions with lysosome-related organelle biogenesis and intracellular trafficking processes. Compounds such as Bafilomycin A1, Chloroquine, Monensin, and NH4Cl modulate lysosomal function and acidification, crucial aspects of BLP2's role in organelle biogenesis. By influencing lysosomal pH and ionic gradients, these compounds underscore the importance of BLP2 in the trafficking and sorting of proteins to lysosome-related organelles.
Microtubule-targeting agents like Nocodazole and Vinblastine, along with cytoskeletal inhibitors such as Latrunculin A and Cytochalasin D, play a key role in enhancing BLP2's activity by altering the dynamics of the cellular trafficking machinery. These compounds disrupt microtubule and actin filament dynamics, thereby impacting the intracellular transport processes crucial for BLP2 function. Additionally, inhibitors of key signaling pathways and cellular processes, including Wortmannin (PI3K inhibitor), Rapamycin (mTOR inhibitor), Dynasore (dynamin inhibitor), and E-64 (cysteine protease inhibitor), contribute to the modulation of BLP2 activity.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Bafilomycin A1 | 88899-55-2 | sc-201550 sc-201550A sc-201550B sc-201550C | 100 µg 1 mg 5 mg 10 mg | $98.00 $255.00 $765.00 $1457.00 | 280 | |
Bafilomycin A1, a V-ATPase inhibitor, can enhance BLP2 activity by affecting lysosomal acidification, which is crucial for BLP2's role in organelle biogenesis. | ||||||
Chloroquine Sulphate | 132-73-0 | sc-337629 | 25 mg | $224.00 | 2 | |
Chloroquine, an autophagy inhibitor, could indirectly increase BLP2 activity by affecting lysosomal function and autophagic flux. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin, an mTOR inhibitor, may indirectly affect BLP2 by modulating autophagy, a process linked to lysosome-related organelle biogenesis. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Latrunculin A, an actin polymerization inhibitor, could enhance BLP2's activity by affecting cytoskeletal dynamics and thus impacting trafficking processes. | ||||||
E-64 | 66701-25-5 | sc-201276 sc-201276A sc-201276B | 5 mg 25 mg 250 mg | $281.00 $947.00 $1574.00 | 14 | |
E-64, a cysteine protease inhibitor, can affect lysosomal function, potentially enhancing BLP2’s role in lysosome-related organelle biogenesis. | ||||||
FCM Lysing solution (1x) | sc-3621 | 150 ml | $62.00 | 8 | ||
Ammonium chloride, a weak base, can influence lysosomal pH, potentially affecting BLP2's function in organelle biogenesis. | ||||||