Chloroquine Sulphate (CAS 132-73-0)
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Chloroquine Sulphate is extensively used in molecular biology research as a tool to understand the accumulation and effects of compounds in lysosomes. Its ability to raise the pH in intracellular compartments is leveraged to study the impact on lysosomal enzyme activity and the processing of proteins and other macromolecules. Additionally, Chloroquine Sulphate is utilized in autophagy research, where it acts as an inhibitor that can help delineate the stages of autophagic flux and understand the mechanisms involved in cellular degradation pathways. In cell biology, it serves as a useful agent in examining endocytic and exocytic processes by disrupting normal vesicular trafficking. Chloroquine Sulphate is also a subject of interest in the field of parasitology, where researchers use it to study the life cycle of parasites and their interactions with host cells.
Chloroquine Sulphate (CAS 132-73-0) References
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- Is a combine therapy of aqueous extract of azadirachta indica leaf (neem leaf) and chloroquine sulphate toxic to the histology of the rabbit cerebellum? | Ucheya, R., et al. 2011. Ann Med Health Sci Res. 1: 203-14. PMID: 23209976
- The in-vitro and ex-vivo effects of chloroquine sulphate on platelet function: implications for malaria prophylaxis in patients with impaired haemostasis. | Cummins, D., et al. 1990. J Trop Med Hyg. 93: 112-5. PMID: 2325191
- Passage of chloroquine into semen. | Ette, EI., et al. 1988. Br J Clin Pharmacol. 26: 179-82. PMID: 3207554
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- The ototoxicity of chloroquine sulphate in the guinea pig. | Sykes, H. 1984. Br J Audiol. 18: 59-69. PMID: 6733318
- Chloroquine reduces blood pressure and forearm vascular resistance and increases forearm blood flow in healthy young adults. | Anigbogu, CN., et al. 1993. Clin Physiol. 13: 209-16. PMID: 8453873
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Chloroquine Sulphate, 25 mg | sc-337629 | 25 mg | $224.00 |