TM2 domain containing 2 (TM2D2) is a protein encoded by the TM2D2 gene in humans. The protein is part of the TM2D family, which is characterized by the presence of a transmembrane 2 (TM2) domain. Proteins with TM2 domains typically span cellular membranes and are involved in various cellular processes including signaling, transport, and cellular interactions.TM2D2, like its family members, is thought to function at the interface of intracellular and extracellular environments. Through its transmembrane domain, TM2D2 can participate in the transmission of signals across the cell membrane, potentially interacting with other membrane proteins, cytoplasmic signaling molecules, or extracellular ligands. The exact biological role of TM2D2 remains to be fully elucidated, but it is speculated to be involved in processes such as cell adhesion, growth, or differentiation based on the functions commonly associated with TM2 domain-containing proteins.
The expression pattern of TM2D2 in various tissues can provide insights into its functional roles. For instance, if TM2D2 is highly expressed in neural tissue, it may imply a role in neurodevelopment or synaptic function. Conversely, if it is present in immune cells, it could suggest a role in immune signaling or cell migration.Studying TM2D2 and its interactions within the cell membrane is critical for understanding the complex network of cellular communication. Aberrations in such proteins can lead to disruptions in signaling pathways and may be implicated in the development of diseases.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitors could indirectly affect TM2D2 by modulating membrane-associated signaling pathways. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PKC activators might influence TM2D2 indirectly through membrane-linked signaling cascades. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $58.00 $170.00 | 15 | |
As modulators of calcium influx, these agents could impact membrane-associated processes potentially involving TM2D2. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitors might indirectly impact TM2D2 through their role in cell growth and membrane-associated processes. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Src kinase inhibitors could affect TM2D2 indirectly by modulating signaling pathways linked to membrane dynamics. | ||||||
Propranolol | 525-66-6 | sc-507425 | 100 mg | $180.00 | ||
GPCR modulators might influence TM2D2 activity indirectly through membrane-associated signaling pathways. | ||||||
Imatinib | 152459-95-5 | sc-267106 sc-267106A sc-267106B | 10 mg 100 mg 1 g | $25.00 $117.00 $209.00 | 27 | |
Tyrosine kinase inhibitors could indirectly impact TM2D2 by affecting signaling pathways associated with membrane proteins. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionophores, by altering ion gradients across membranes, might indirectly affect the function of membrane-associated proteins like TM2D2. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $87.00 | 44 | |
These compounds can influence membrane trafficking, potentially affecting TM2D2's function or localization. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
By impacting autophagic processes,these inhibitors could indirectly influence membrane dynamics and protein turnover, potentially affecting TM2D2. | ||||||