BFZB Activators
Ubiquinol-cytochrome c reductase complex assembly factor 1, often abbreviated as UQCC1, is an essential protein implicated in the mitochondrial respiratory chain, specifically within the context of complex III assembly. Complex III, also known as the cytochrome bc1 complex or ubiquinol-cytochrome c oxidoreductase, is a critical component of the mitochondrial electron transport chain that generates the electrochemical gradient used to produce ATP, the cell's energy currency.
UQCC1 is involved in the early stages of complex III assembly, where it plays a pivotal role in the stabilization of pre-complexes that precede the formation of the fully functional complex III. The exact mechanism through which UQCC1 facilitates the assembly is not fully elucidated, but it is known to interact with other assembly factors and core components of the complex, suggesting a direct role in the proper integration of these subunits into the nascent complex.Mutations or deficiencies in UQCC1 can lead to disorders related to mitochondrial function, as the proper assembly and function of complex III are paramount for oxidative phosphorylation. Manifestations of such deficiencies are typically multisystemic, reflecting the critical role of mitochondria in various tissues. These phenotypes underscore UQCC1's importance in maintaining the integrity of mitochondrial respiration.
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $71.00 $184.00 | 1 | |
Coenzyme Q10 is a key component of the electron transport chain and may support the function of complex III, potentially influencing UQCC1. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol has been shown to enhance mitochondrial biogenesis and function, which might indirectly affect UQCC1. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Metformin can influence mitochondrial function and has been suggested to have an impact on respiratory chain complexes. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $31.00 $46.00 $122.00 $204.00 | 5 | |
Bezafibrate is known to stimulate mitochondrial biogenesis, potentially affecting the activity of complexes like CIII. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR is known to activate AMPK, leading to enhanced mitochondrial biogenesis and potentially influencing UQCC1. | ||||||
SRT1720 | 1001645-58-4 | sc-364624 sc-364624A | 5 mg 10 mg | $197.00 $364.00 | 13 | |
Sirtuin activators like SRT1720 can enhance mitochondrial function, possibly affecting UQCC1. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $110.00 $150.00 $220.00 $300.00 $600.00 | 4 | |
NMN, a NAD+ precursor, is involved in enhancing mitochondrial function, which might indirectly influence UQCC1. | ||||||
Nicotinamide riboside | 1341-23-7 | sc-507345 | 10 mg | $411.00 | ||
NR, another NAD+ precursor, has been shown to support mitochondrial health, potentially affecting UQCC1. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $55.00 $125.00 | 13 | |
PGC-1α agonists like Pioglitazone can induce mitochondrial biogenesis, possibly impacting UQCC1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin can influence mitochondrial dynamics and has been shown to affect respiratory chain complexes. | ||||||