β2B Tubulin Inhibitors belong to a class of chemical compounds that specifically target and interact with β2B tubulin, a critical protein component of microtubules in cells. Microtubules are dynamic structures essential for various cellular processes, including cell division, intracellular transport, and maintenance of cell shape. β2B tubulin is a specialized isoform of tubulin, a family of proteins that make up the building blocks of microtubules. Inhibitors of β2B tubulin play a pivotal role in understanding the intricacies of microtubule dynamics and can be valuable tools in both basic research and drug development.
The mechanism of action of β2B Tubulin Inhibitors involves binding to β2B tubulin and interfering with the assembly and stability of microtubules. By doing so, these compounds disrupt essential cellular processes that rely on microtubules, such as mitosis and intracellular transport. This disruption can lead to various cellular consequences, making β2B Tubulin Inhibitors significant inresearch. Moreover, it serves as lead compounds for drug development since aberrant microtubule function is a hallmark of several diseases, especially various forms of cancer. Researchers are continually exploring the chemical diversity within this class to discover novel compounds with enhanced specificity and efficacy, which can pave the way for further insights into cellular biology and the development of new therapies.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Binds to β2B tubulin, disrupting microtubule assembly and function. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Binds to tubulin and prevents microtubule polymerization. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Depolymerizes microtubules by binding to tubulin subunits. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $84.00 | 1 | |
Inhibits microtubule assembly by binding to tubulin. | ||||||
Griseofulvin | 126-07-8 | sc-202171A sc-202171 sc-202171B | 5 mg 25 mg 100 mg | $85.00 $220.00 $598.00 | 4 | |
Binds to tubulin and interferes with microtubule function. | ||||||
Combrestatin A4 | 117048-59-6 | sc-204697 sc-204697A | 1 mg 5 mg | $46.00 $81.00 | ||
Disrupts microtubules and affects vascular function. | ||||||
Colchiceine | 477-27-0 | sc-207452 | 10 mg | $359.00 | ||
Inhibits microtubule assembly by binding to tubulin. | ||||||
Estramustine | 2998-57-4 | sc-353281 sc-353281A | 100 mg 1 g | $265.00 $743.00 | ||
Combines microtubule inhibition with hormonal effects. | ||||||