The β-1,3-Gal-T4, known as B3GALT4, belongs to the β-1,3-galactosyltransferase family, playing a pivotal role in the glycosylation processes of cells. Its activity is at the crossroads of intricate biochemical pathways, and understanding the nuances of this activity offers insight into cellular functions. Certain chemicals, such as UDP-Glucose, stand as direct substrates for many galactosyltransferases. The availability of such substrates is paramount for maintaining and possibly increasing B3GALT4 activity. Likewise, molecules like Mannose and N-Acetylglucosamine play crucial roles in glycosylation, with their presence modulating the action of B3GALT4.
Additionally, cellular signaling compounds such as Forskolin, which heightens intracellular cAMP levels, can have downstream effects on various processes, including glycosylation. This ripple effect suggests that alterations in cellular signaling can pave the way for a change in B3GALT4 activity. Furthermore, the glycosylation landscape is influenced by agents like Tunicamycin and Swainsonine, which affect N-linked glycosylation and mannose processing, respectively. Such modulations in glycosylation can indirectly sway B3GALT4 activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
D-Mannose | 3458-28-4 | sc-211180 sc-211180A | 100 g 250 g | $103.00 $161.00 | 1 | |
Can influence glycosylation processes and potentially modulate B3GALT4 activity. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Raises intracellular cAMP levels, which can affect various cellular processes, including glycosylation. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Influences various cell signaling processes that might affect glycosylation and B3GALT4 activity. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $126.00 $328.00 | 30 | |
An analog of cAMP, can modulate cellular processes that could influence B3GALT4 function. | ||||||
N-Acetyl-D-glucosamine | 7512-17-6 | sc-286377 sc-286377B sc-286377A | 50 g 100 g 250 g | $94.00 $162.00 $306.00 | 1 | |
Involved in O-GlcNAcylation and can potentially influence B3GALT4's glycosylation activity. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
Inhibits N-linked glycosylation but can indirectly affect overall glycosylation patterns, impacting B3GALT4. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Proteasome inhibitor which can affect protein turnover and impact glycosylation indirectly. | ||||||
Fucoidan | 9072-19-9 | sc-255187 sc-255187A | 5 g 10 g | $190.00 $318.00 | 7 | |
A complex sulfated polysaccharide that can influence various cell signaling and glycosylation processes. | ||||||