BC061212 Inhibitors
BC061212, a protein intricately linked to the Wnt/β-catenin signaling pathway, plays a pivotal role in cellular processes, including cell fate determination and tissue homeostasis. This class of inhibitors targets glycogen synthase kinase-3 (GSK-3) and protein kinase C beta (PKCβ) to modulate BC061212 expression and function indirectly. GSK-3 inhibitors, including SB-216763, GSK-3 Inhibitor XVI, GSK-3 Inhibitor IX, Tideglusib, LY2090314, CHIR-99023, 9-ING-41, AZD1080, GSK-3β Inhibitor VIII, and SB-415286, form the primary category of BC061212 inhibitors. These compounds interfere with GSK-3, a critical component of the Wnt/β-catenin signaling pathway. By inhibiting GSK-3, these compounds disrupt the degradation of β-catenin, leading to its accumulation in the cytoplasm and subsequent translocation into the nucleus. This process enhances Wnt/β-catenin signaling, influencing the expression of genes involved in cellular processes such as embryonic development, tissue regeneration, and cell proliferation.
Enzastaurin, a PKCβ inhibitor, represents an additional facet of BC061212 modulation. By targeting PKCβ, Enzastaurin influences the PI3K/Akt pathway, potentially impacting BC061212 expression and function. This regulatory mechanism connects PKCβ inhibition to cellular processes like cell survival and proliferation. In summary, BC061212 inhibitors provide valuable tools for unraveling the intricate molecular pathways governed by Wnt/β-catenin signaling. These compounds offer insights into the potential implications of BC061212 modulation, shedding light on its crucial role in fundamental cellular processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB-216763 | 280744-09-4 | sc-200646 sc-200646A | 1 mg 5 mg | $71.00 $202.00 | 18 | |
SB-216763 inhibits glycogen synthase kinase-3 (GSK-3), potentially influencing BC061212 indirectly. This interference may impact BC061212 expression and function by modulating the Wnt/β-catenin signaling pathway, a key regulator of cellular processes, including cell proliferation and differentiation. | ||||||
GSK-3 Inhibitor XVI | 252917-06-9 | sc-221691 sc-221691A | 5 mg 25 mg | $180.00 $610.00 | 4 | |
GSK-3 Inhibitor XVI targets glycogen synthase kinase-3 (GSK-3), potentially modulating BC061212 expression and function. This interference may impact the Wnt/β-catenin signaling pathway, suggesting a role in cellular processes such as cell fate determination and tissue homeostasis. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $58.00 $188.00 $884.00 | 10 | |
GSK-3 Inhibitor IX inhibits glycogen synthase kinase-3 (GSK-3), potentially influencing BC061212 indirectly. This interference may modulate BC061212 expression and function by affecting the Wnt/β-catenin signaling pathway, an intricate regulator of cellular processes, including embryonic development and tissue regeneration. | ||||||
Tideglusib | 865854-05-3 | sc-507358 | 10 mg | $77.00 | ||
Tideglusib targets glycogen synthase kinase-3 (GSK-3), potentially modulating BC061212 expression and function. This interference may impact the Wnt/β-catenin signaling pathway, highlighting its role in cellular processes such as stem cell maintenance and tissue repair. | ||||||
LY2090314 | 603288-22-8 | sc-507359 | 5 mg | $175.00 | ||
LY2090314 inhibits glycogen synthase kinase-3 (GSK-3), potentially influencing BC061212 indirectly. This interference may impact BC061212 expression and function by modulating the Wnt/β-catenin signaling pathway, contributing to the regulation of cell proliferation and tissue homeostasis. | ||||||
AZD1080 | 612487-72-6 | sc-503187 | 2.5 mg | $280.00 | ||
AZD1080 targets glycogen synthase kinase-3 (GSK-3), potentially influencing BC061212 indirectly. This interference may modulate BC061212 expression and function by affecting the Wnt/β-catenin signaling pathway, highlighting its role in cellular processes such as embryonic development and tissue regeneration. | ||||||
GSK-3β Inhibitor VIII | 487021-52-3 | sc-202636 sc-202636A | 5 mg 10 mg | $134.00 $150.00 | 5 | |
GSK-3β Inhibitor VIII inhibits glycogen synthase kinase-3 (GSK-3), potentially modulating BC061212 expression and function. This interference may impact the Wnt/β-catenin signaling pathway, contributing to the regulation of cellular processes such as cell proliferation and tissue homeostasis. | ||||||
Enzastaurin | 170364-57-5 | sc-364488 sc-364488A sc-364488B | 10 mg 50 mg 200 mg | $259.00 $612.00 $1721.00 | 3 | |
Enzastaurin targets protein kinase C beta (PKCβ), potentially influencing BC061212 indirectly. This interference may impact BC061212 expression and function by modulating the PI3K/Akt pathway, contributing to the regulation of cellular processes such as cell survival and proliferation. | ||||||