BACH2 Inhibitors
The chemical class BACH2 Inhibitors refers to compounds that can indirectly inhibit the transcription regulator protein BACH2 by influencing cellular processes or pathways that BACH2 is involved in, such as the oxidative stress response. BACH2 activity is known to be repressed under conditions of reduced oxidative stress. Therefore, substances that can induce such a state, known as antioxidants, can be considered indirect inhibitors of BACH2. Antioxidants are compounds that can neutralize reactive oxygen species (ROS), thereby reducing oxidative stress.
Examples of these antioxidants include ascorbic acid (vitamin C), alpha-tocopherol (vitamin E), glutathione, and N-acetylcysteine. Ascorbic acid and alpha-tocopherol are potent antioxidants that can neutralize ROS, while glutathione and N-acetylcysteine can increase the cellular capacity to neutralize these species. Other substances with antioxidant properties include resveratrol, curcumin, epigallocatechin gallate, quercetin, lycopene, and beta-carotene. These compounds can neutralize ROS directly or enhance the cellular antioxidant defenses, thereby reducing oxidative stress and potentially inhibiting BACH2.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $45.00 | 5 | |
Ascorbic acid is a potent antioxidant that can reduce oxidative stress, potentially leading to the inhibition of BACH2. | ||||||
(+)-α-Tocopherol | 59-02-9 | sc-214454 sc-214454A sc-214454B | 10 g 25 g 100 g | $42.00 $61.00 $138.00 | ||
Alpha-Tocopherol is an antioxidant that can reduce oxidative stress, potentially leading to the inhibition of BACH2. | ||||||
Glutathione, reduced | 70-18-8 | sc-29094 sc-29094A | 10 g 1 kg | $76.00 $2050.00 | 8 | |
Glutathione is a tripeptide that acts as an antioxidant, reducing oxidative stress and potentially inhibiting BACH2. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
N-Acetylcysteine is a precursor to glutathione and is known to reduce oxidative stress, potentially leading to the inhibition of BACH2. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is a plant compound with antioxidant properties, it reduces oxidative stress and could potentially inhibit BACH2. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin is a compound from turmeric that has antioxidant properties, reducing oxidative stress and potentially leading to BACH2 inhibition. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Epigallocatechin gallate is a catechin found in green tea with antioxidant properties, reducing oxidative stress and potentially inhibiting BACH2. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin is a flavonoid with antioxidant properties found in many plants and foods, it reduces oxidative stress and could potentially inhibit BACH2. | ||||||
Lycopene | 502-65-8 | sc-205738 sc-205738A sc-205738B | 1 mg 5 mg 1 g | $143.00 $571.00 $6125.00 | 4 | |
Lycopene is a carotenoid found in tomatoes and other red fruits and vegetables, it has antioxidant properties and can reduce oxidative stress, potentially leading to BACH2 inhibition. | ||||||
β-Carotene | 7235-40-7 | sc-202485 sc-202485A sc-202485B sc-202485C | 1 g 25 g 50 g 5 kg | $68.00 $297.00 $502.00 $12246.00 | 5 | |
Beta-Carotene is a carotenoid that acts as an antioxidant, reducing oxidative stress and potentially inhibiting BACH2. | ||||||