BABAM1 inhibitors are a class of chemical compounds that specifically target and modulate the activity of the protein called BABAM1, also known as BRISC and SHMT2. BABAM1 is a key component of the BRISC complex, which plays an essential role in cellular processes such as DNA repair, inflammation, and immune response. The inhibitors act by binding to BABAM1 and altering its conformation or interfering with its interaction with other proteins within the complex. This modulation of BABAM1 activity can have significant effects on cellular signaling pathways and molecular interactions.
BABAM1 inhibitors are designed to exert precise control over the function of BABAM1, thereby influencing downstream cellular processes. By selectively inhibiting BABAM1, these compounds offer a tool for researchers to investigate the mechanisms by which the BRISC complex and associated pathways operate. The inhibitors can help elucidate the complex regulatory networks involving protein interactions and signaling cascades. In the research setting, BABAM1 inhibitors can serve as valuable probes to explore the physiological and molecular consequences of modulating BABAM1 activity. The development and study of BABAM1 inhibitors have the potential to uncover novel insights into cellular processes and their underlying molecular mechanisms. Understanding the intricacies of the BRISC complex and the role of BABAM1 within it can have broad implications for various fields, including cell biology, immunology, and cancer research. By precisely manipulating the activity of BABAM1, researchers may gain a better understanding of how this protein contributes to disease states, immune responses, and the maintenance of genomic stability.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
MLN 4924 | 905579-51-3 | sc-484814 | 1 mg | $286.00 | 1 | |
Inhibits NEDD8-activating enzyme (NAE), which affects protein degradation and DNA repair pathways. | ||||||
Veliparib | 912444-00-9 | sc-394457A sc-394457 sc-394457B | 5 mg 10 mg 50 mg | $182.00 $275.00 $726.00 | 3 | |
PARP (Poly ADP-ribose polymerase) inhibitor used in cancer therapy, involved in DNA repair processes. | ||||||
Olaparib | 763113-22-0 | sc-302017 sc-302017A sc-302017B | 250 mg 500 mg 1 g | $210.00 $305.00 $495.00 | 10 | |
Another PARP inhibitor used in cancer therapy. | ||||||
Rucaparib | 283173-50-2 | sc-507419 | 5 mg | $150.00 | ||
PARP inhibitor used primarily for ovarian cancer. | ||||||
Talazoparib | 1207456-01-6 | sc-507440 | 10 mg | $795.00 | ||
PARP inhibitor studied in the research of certain types of breast cancer. | ||||||
Niraparib | 1038915-60-4 | sc-507492 | 10 mg | $150.00 | ||
PARP inhibitor studied in the research of ovarian and other types of cancer. | ||||||
Ceralasertib | 1352226-88-0 | sc-507439 | 10 mg | $573.00 | ||
Inhibits Ataxia Telangiectasia and Rad3-related protein (ATR), involved in DNA damage response and repair. | ||||||
ATM Kinase Inhibitor | 587871-26-9 | sc-202963 | 2 mg | $110.00 | 28 | |
Inhibits ATM kinase, involved in DNA damage response and repair. | ||||||