ATXN7L2 Activators encompass a range of chemical compounds that indirectly facilitate the functional activity of ATXN7L2, primarily through their effects on chromatin remodeling and transcription regulation. HDAC inhibitors such as Trichostatin A, Vorinostat, Valproic Acid, Sodium Butyrate, Romidepsin, Panobinostat, Scriptaid, and MS-275 play a crucial role in enhancing ATXN7L2's activity. These inhibitors lead to increased histone acetylation, thereby loosening chromatin structure and enhancing the transcriptional regulation capabilities of ATXN7L2. By altering the chromatin landscape, these compounds aid ATXN7L2 in its role of facilitating gene expression, crucial for various cellular functions.
In addition to HDAC inhibitors, compounds like Anacardic Acid, Curcumin, Caffeic Acid Phenethyl Ester, and Sirtinol also contribute to the modulation of ATXN7L2 activity. These compounds influence histone modification patterns and transcription factor activity, indirectly affecting ATXN7L2's role in chromatin remodeling and gene regulation. The diverse mechanisms of these activators reflect the multifaceted nature of ATXN7L2's function in transcription regulation. Collectively, these ATXN7L2 Activators, through their targeted effects on chromatin dynamics and gene expression, facilitate the enhancement of ATXN7L2-mediated functions in the cell.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Vorinostat, an HDAC inhibitor, could augment ATXN7L2's role in chromatin remodeling and transcription regulation. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic Acid, also an HDAC inhibitor, potentially enhances ATXN7L2 activity by affecting chromatin structure and gene expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium Butyrate, an HDAC inhibitor, can influence ATXN7L2 by altering histone acetylation and chromatin accessibility. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $218.00 $634.00 | 1 | |
Romidepsin, a potent HDAC inhibitor, may enhance ATXN7L2's functional activity in transcription regulation by modulating chromatin structure. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $200.00 | 9 | |
Panobinostat, another HDAC inhibitor, could indirectly enhance ATXN7L2 activity by influencing histone acetylation and gene expression. | ||||||
Anacardic Acid | 16611-84-0 | sc-202463 sc-202463A | 5 mg 25 mg | $102.00 $204.00 | 13 | |
Anacardic Acid, a histone acetyltransferase inhibitor, may indirectly influence ATXN7L2 by altering histone modification patterns. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, known for its effect on histone acetylation, could modulate ATXN7L2 activity in chromatin remodeling and gene regulation. | ||||||
Caffeic acid phenethyl ester | 104594-70-9 | sc-200800 sc-200800A sc-200800B | 20 mg 100 mg 1 g | $71.00 $296.00 $612.00 | 19 | |
CAPE, an inhibitor of NF-kB, can indirectly affect ATXN7L2 activity through pathways involved in inflammation and gene expression. | ||||||
Sirtinol | 410536-97-9 | sc-205976 sc-205976A | 1 mg 5 mg | $38.00 $113.00 | 14 | |
Sirtinol, a sirtuin inhibitor, could affect ATXN7L2 by modulating pathways involved in histone deacetylation and transcription regulation. | ||||||
Scriptaid | 287383-59-9 | sc-202807 sc-202807A | 1 mg 5 mg | $64.00 $183.00 | 11 | |
Scriptaid, an HDAC inhibitor, may enhance ATXN7L2's role in chromatin remodeling and transcriptional regulation. | ||||||