Date published: 2026-3-24

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ASC-1 Inhibitors

Asc-1 inhibitors, also known as alanine-serine-cysteine-1 inhibitors, are a class of small molecules or compounds that target a specific cellular mechanism involving the Asc-1 protein. Asc-1, short for alanine-serine-cysteine-1 transporter, is a membrane protein primarily found in the cells of the central nervous system, including neurons and glial cells. This protein plays a pivotal role in the regulation of amino acid homeostasis within these cells, which is crucial for the proper functioning of the nervous system. Asc-1 inhibitors are designed to modulate the activity of this protein, either by blocking or reducing its function, and are thus important in the context of understanding cellular physiology and potential implications in various biological processes. At the molecular level, Asc-1 inhibitors typically interact with specific binding sites on the Asc-1 protein. By doing so, they can interfere with the transport of amino acids across the cell membrane, leading to disruptions in the intracellular amino acid concentrations. This modulation can have cascading effects on various cellular processes, including protein synthesis, neurotransmitter production, and cell signaling pathways. Researchers and scientists often use Asc-1 inhibitors as experimental tools to elucidate the intricate details of amino acid transport and its impact on cellular physiology. Understanding the role of Asc-1 and its inhibitors can provide valuable insights into the broader fields of neuroscience and cell biology, as it pertains to amino acid metabolism and the fine-tuning of cellular functions.

Items 1 to 10 of 13 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

L-Arginine

74-79-3sc-391657B
sc-391657
sc-391657A
sc-391657C
sc-391657D
5 g
25 g
100 g
500 g
1 kg
$20.00
$31.00
$61.00
$219.00
$352.00
2
(0)

L-arginine is an amino acid that has been shown to increase the expression and activity of ASC-1 in certain cell types.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$80.00
$220.00
$460.00
64
(2)

Can inhibit cellular pathways that ASC-1 is part of, possibly modulating ASC-1 activity.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Targets mTOR signaling, which can indirectly affect ASC-1 related pathways.

L-Leucine

61-90-5sc-364173
sc-364173A
25 g
100 g
$21.00
$62.00
(0)

Leucine, another amino acid, is known to stimulate ASC-1 activity, particularly in muscle cells.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

A PI3K inhibitor; PI3K pathways are known to interact with those of ASC-1.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$156.00
$1248.00
$12508.00
82
(1)

Insulin, a hormone produced by the pancreas, can modulate the activity of ASC-1 and enhance amino acid uptake in various tissues.

L-Glutamine

56-85-9sc-391013
sc-391013C
sc-391013A
sc-391013D
sc-391013B
100 g
250 g
1 kg
5 kg
10 kg
$37.00
$47.00
$99.00
$379.00
$733.00
2
(0)

Glutamine, an amino acid, can affect ASC-1 function and amino acid transport in certain cell types.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

MEK inhibitor; can influence ERK signaling which is upstream of ASC-1 related pathways.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

JNK inhibitor; by inhibiting JNK, it can indirectly affect pathways related to ASC-1.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

Another MEK inhibitor; can modulate ERK signaling upstream of ASC-1 pathways.