Date published: 2025-11-29

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APPL CRISPR Plasmids

Santa Cruz Biotechnology, Inc. offers a broad range of gene editing products including CRISPR/Cas9 Knockout and CRISPR Double Nickase plasmids for gene silencing. APPL gene silencers are available as APPL CRISPR/Cas9 Knockout plasmids and APPL Double Nickase Plasmids. APPL CRISPR/dCas9 Activation Plasmids and CRISPR Lenti Activation Systems for gene activation are also available. Gene silencers and activators are useful for gene studies in combination with antibodies used for protein detection.

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APPL CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

APPL1 CRISPR/Cas9 KO Plasmid (h)

sc-402243hGene KnockoutGFP0
(0)

APPL1 HDR Plasmid (h)

sc-402243-HDRhHomology Directed RepairPuromycin0
(0)

APPL1 Double Nickase Plasmid (h)

sc-402243-NIChGene KnockoutPuromycin0
(0)

APPL1 Double Nickase Plasmid (h2)

sc-402243-NIC-2hGene KnockoutPuromycin0
(0)

APPL1 CRISPR/Cas9 KO Plasmid (m)

sc-428481mGene KnockoutGFP0
(0)

APPL1 HDR Plasmid (m)

sc-428481-HDRmHomology Directed RepairPuromycin0
(0)

APPL1 Double Nickase Plasmid (m)

sc-428481-NICmGene KnockoutPuromycin0
(0)

APPL1 Double Nickase Plasmid (m2)

sc-428481-NIC-2mGene KnockoutPuromycin0
(0)

APPL2 CRISPR/Cas9 KO Plasmid (h)

sc-402991hGene KnockoutGFP0
(0)

APPL2 HDR Plasmid (h)

sc-402991-HDRhHomology Directed RepairPuromycin0
(0)

APPL2 Double Nickase Plasmid (h)

sc-402991-NIChGene KnockoutPuromycin0
(0)

APPL2 Double Nickase Plasmid (h2)

sc-402991-NIC-2hGene KnockoutPuromycin0
(0)

APPL2 CRISPR/Cas9 KO Plasmid (m)

sc-432068mGene KnockoutGFP0
(0)

APPL2 HDR Plasmid (m)

sc-432068-HDRmHomology Directed RepairPuromycin0
(0)

APPL2 Double Nickase Plasmid (m)

sc-432068-NICmGene KnockoutPuromycin0
(0)

APPL2 Double Nickase Plasmid (m2)

sc-432068-NIC-2mGene KnockoutPuromycin0
(0)

APPL CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

APPL1 CRISPR Activation Plasmid (h)

sc-402243-ACThGene ActivationPuro, Blast, Hygro0
(0)

APPL1 CRISPR Activation Plasmid (h2)

sc-402243-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

APPL1 Lentiviral Activation Particles (h)

sc-402243-LAChGene ActivationPuro, Blast, Hygro0
(0)

APPL1 Lentiviral Activation Particles (h2)

sc-402243-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

APPL1 CRISPR Activation Plasmid (m)

sc-428481-ACTmGene ActivationPuro, Blast, Hygro0
(0)

APPL1 CRISPR Activation Plasmid (m2)

sc-428481-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

APPL1 Lentiviral Activation Particles (m)

sc-428481-LACmGene ActivationPuro, Blast, Hygro0
(0)

APPL1 Lentiviral Activation Particles (m2)

sc-428481-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

APPL2 CRISPR Activation Plasmid (h)

sc-402991-ACThGene ActivationPuro, Blast, Hygro0
(0)

APPL2 CRISPR Activation Plasmid (h2)

sc-402991-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

APPL2 Lentiviral Activation Particles (h)

sc-402991-LAChGene ActivationPuro, Blast, Hygro0
(0)

APPL2 Lentiviral Activation Particles (h2)

sc-402991-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

APPL2 CRISPR Activation Plasmid (m)

sc-432068-ACTmGene ActivationPuro, Blast, Hygro0
(0)

APPL2 CRISPR Activation Plasmid (m2)

sc-432068-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

APPL2 Lentiviral Activation Particles (m)

sc-432068-LACmGene ActivationPuro, Blast, Hygro0
(0)

APPL2 Lentiviral Activation Particles (m2)

sc-432068-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)