apoC-II Activators
apoC-II Activators encompass a variety of compounds that indirectly enhance the functional activity of apoC-II, primarily through their roles in lipid metabolism and the modulation of lipoprotein lipase (LPL), a key enzyme activated by apoC-II. Omega-3 fatty acids, such as Eicosapentaenoic Acid and Docosahexaenoic Acid, are pivotal in this aspect. They improve lipid profiles and promote LPL activation, thereby enhancing the action of apoC-II in lipid processing. Similarly, Niacin, Fenofibrate, and Gemfibrozil also contribute to the activation of apoC-II. Niacin influences lipid metabolism, which can increase the demand for apoC-II's activity. Fenofibrate and Gemfibrozil, as fibrate drugs, elevate LPL activity, a process where apoC-II serves as a crucial cofactor, leading to more efficient lipid clearance.
Additionally, compounds such as Green Tea Extract (specifically Epigallocatechin Gallate), Orlistat, Statins (Atorvastatin and Rosuvastatin), L-Carnitine, Alpha-Lipoic Acid, and Linoleic Acid play significant roles in modulating lipid metabolism and, in turn, apoC-II activity. Epigallocatechin Gallate from green tea can indirectly boost apoC-II activity by impacting lipid metabolism pathways. Orlistat, by altering lipid absorption, influences the lipid metabolism in which apoC-II is involved. Statins, known for their cholesterol-lowering effects, indirectly influence apoC-II activity by modifying lipoprotein profiles, potentially affecting LPL activation. L-Carnitine facilitates the transport of fatty acids into mitochondria, indirectly impacting apoC-II's role in lipid metabolism. Alpha-Lipoic Acid improves lipid metabolism, thereby potentially enhancing apoC-II efficiency. Lastly, Linoleic Acid, a polyunsaturated fatty acid, influences lipid profiles, which can lead to increased LPL function and, consequently, enhanced activity of apoC-II. Together, these apoC-II Activators, by targeting various aspects of lipid metabolism and LPL activation, facilitate the enhanced functional efficiency of apoC-II, crucial for proper lipid processing and metabolic balance.
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Docosa-4Z,7Z,10Z,13Z,16Z,19Z-hexaenoic Acid (22:6, n-3) | 6217-54-5 | sc-200768 sc-200768A sc-200768B sc-200768C sc-200768D | 100 mg 1 g 10 g 50 g 100 g | $92.00 $206.00 $1744.00 $7864.00 $16330.00 | 11 | |
Docosahexaenoic Acid, another omega-3 fatty acid, indirectly activates apoC-II by improving lipid metabolism and aiding in the activation of LPL, which is stimulated by apoC-II. | ||||||
Nicotinic Acid | 59-67-6 | sc-205768 sc-205768A | 250 g 500 g | $61.00 $122.00 | 1 | |
Niacin influences lipid metabolism, thereby indirectly enhancing apoC-II activity by promoting the mobilization and breakdown of lipids where apoC-II plays a role. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
Fenofibrate, a fibric acid derivative, enhances apoC-II activity by upregulating LPL activity, which in turn is activated by apoC-II, leading to improved lipid clearance. | ||||||
Gemfibrozil | 25812-30-0 | sc-204764 sc-204764A | 5 g 25 g | $65.00 $262.00 | 2 | |
Gemfibrozil, another fibrate, indirectly activates apoC-II by increasing LPL activity, thus enhancing the functional role of apoC-II in lipid metabolism. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
Epigallocatechin Gallate, found in green tea, can enhance apoC-II activity indirectly by influencing lipid metabolism, which can lead to increased LPL activity, a process where apoC-II is a cofactor. | ||||||
Lipase Inhibitor, THL | 96829-58-2 | sc-203108 | 50 mg | $51.00 | 7 | |
Orlistat, a lipase inhibitor, indirectly affects apoC-II activity by modifying lipid absorption and metabolism, potentially enhancing the role of apoC-II in lipoprotein metabolism. | ||||||
Atorvastatin | 134523-00-5 | sc-337542A sc-337542 | 50 mg 100 mg | $252.00 $495.00 | 9 | |
Atorvastatin, a statin, can indirectly enhance apoC-II activity by altering cholesterol levels and lipoprotein profiles, which may influence apoC-II-mediated lipid processing. | ||||||
Rosuvastatin | 287714-41-4 | sc-481834 | 10 mg | $142.00 | 8 | |
Rosuvastatin, another statin, indirectly affects apoC-II activity through its lipid-modifying actions, potentially influencing LPL activation, where apoC-II is a key activator. | ||||||
L-Carnitine | 541-15-1 | sc-205727 sc-205727A sc-205727B sc-205727C | 1 g 5 g 100 g 250 g | $23.00 $33.00 $77.00 $175.00 | 3 | |
L-Carnitine enhances apoC-II activity by facilitating fatty acid transport into mitochondria, indirectly influencing lipid metabolism pathways involving apoC-II. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $68.00 $120.00 $208.00 $373.00 $702.00 | 3 | |
Alpha-Lipoic Acid indirectly activates apoC-II by improving overall lipid metabolism, potentially enhancing the efficiency of pathways where apoC-II is involved. | ||||||