Date published: 2026-4-1

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ANXA2R Inhibitors

ANXA2R Inhibitors belong to a specialized chemical class designed to target and modulate the activity of Annexin A2 Receptor (ANXA2R), a cell surface receptor intimately associated with numerous cellular processes. ANXA2R, also known as Annexin A2 Receptor or ANX2R, is a protein receptor found on the surface of various cell types, including endothelial cells and immune cells. Its primary role is to interact with Annexin A2, a multifunctional protein, to mediate diverse cellular functions. The development of ANXA2R Inhibitors is grounded in the understanding of the pivotal role played by ANXA2R in processes such as cell adhesion, migration, and membrane repair.

ANXA2R Inhibitors encompass a diverse range of chemical compounds that are specifically designed to disrupt the binding and activation of ANXA2R by Annexin A2. These inhibitors can function through various mechanisms, including competitive binding at the receptor's active site or interfering with the downstream signaling pathways triggered by ANXA2R activation. By inhibiting ANXA2R, these compounds have the potential to modulate cell adhesion, migration, and other cellular processes that are tightly regulated by ANXA2R-mediated interactions. Research into ANXA2R Inhibitors is driven by the desire to gain a deeper understanding of the molecular mechanisms underlying cell behavior and to explore their potential applications in various fields, including cell biology and drug development. These inhibitors serve as valuable tools for dissecting the intricate web of cellular processes influenced by ANXA2R, shedding light on the fundamental biology of cells and opening avenues for future research and potential applications.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

BMS-265246

582315-72-8sc-364440
sc-364440A
5 mg
10 mg
$304.00
$555.00
(0)

BMS-265246 inhibits ANXA2R by disrupting its interaction with its ligands, preventing downstream signaling pathways involved in cell proliferation and migration.

ML-9

105637-50-1sc-200519
sc-200519A
sc-200519B
sc-200519C
10 mg
50 mg
100 mg
250 mg
$112.00
$449.00
$673.00
$1224.00
2
(1)

ML-9 inhibits ANXA2R by interfering with its calcium-dependent membrane binding, disrupting the receptor's role in cellular membrane organization and endocytosis.

YM 254890

568580-02-9sc-507356
1 mg
$510.00
(0)

YM-254890 selectively inhibits ANXA2R by targeting its G-protein-coupled signaling, disrupting the receptor's involvement in intracellular calcium mobilization and cell motility.

KN-93

139298-40-1sc-202199
1 mg
$182.00
25
(1)

KN-93 inhibits ANXA2R by blocking its calcium-dependent phosphorylation, thereby disrupting the receptor's role in modulating cytoskeletal dynamics and cell adhesion.