Date published: 2025-10-18

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Antitumor

Santa Cruz Biotechnology now offers a broad range of antitumor compounds for use in various applications. Antitumor compounds are chemical agents that inhibit the growth and proliferation of tumor cells, making them indispensable in cancer research. These compounds are pivotal for studying the complex mechanisms underlying tumor development, progression, and metastasis. Researchers use antitumor agents to investigate cellular processes such as apoptosis, cell cycle regulation, and signal transduction pathways that are often dysregulated in cancer cells. By understanding these mechanisms, scientists can identify potential targets for new research and scientific breakthroughs. Antitumor compounds also play a significant role in genetic and molecular biology research, where they are used to study the effects of gene expression changes and mutations on cell growth. Environmental scientists may examine the impact of antitumor compounds as environmental contaminants and their effects on non-target organisms in ecosystems. Additionally, antitumor agents are utilized in agricultural research to explore their potential in controlling plant diseases caused by tumor-like growths. In materials science, antitumor compounds are incorporated into advanced materials for developing innovative diagnostic tools and biosensors. The applications of antitumor compounds in scientific research are vast, ranging from basic studies of cellular biology to the development of novel materials and environmental monitoring techniques. The broad utility of these compounds highlights their importance in advancing our understanding of cancer biology and contributing to innovative solutions in various scientific fields. View detailed information on our available antitumor compounds by clicking on the product name.

Items 131 to 140 of 141 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$68.00
$261.00
8
(1)

Mycophenolic acid exhibits antitumor properties through its selective inhibition of inosine monophosphate dehydrogenase (IMPDH), a key enzyme in the de novo purine synthesis pathway. By disrupting nucleotide synthesis, it effectively hampers the proliferation of neoplastic cells. Its unique interaction with the enzyme leads to a preferential impact on lymphocytes, which are highly dependent on this pathway for growth. This selective targeting results in altered cellular metabolism and growth inhibition in tumor environments.

10-Deacetylbaccatin-III

32981-86-5sc-204607
sc-204607A
5 mg
25 mg
$174.00
$523.00
(0)

10-Deacetylbaccatin-III demonstrates antitumor activity by modulating microtubule dynamics, disrupting the mitotic spindle formation essential for cell division. Its structural conformation allows for effective binding to tubulin, leading to cell cycle arrest in the G2/M phase. This interference with cytoskeletal integrity not only inhibits tumor cell proliferation but also induces apoptosis through the activation of specific signaling pathways, enhancing its efficacy against malignancies.

Ginsenoside Re

52286-59-6sc-205707
sc-205707A
1 mg
5 mg
$57.00
$111.00
(1)

Ginsenoside Re exhibits antitumor properties through its ability to influence cellular signaling pathways and modulate apoptosis. It interacts with various receptors, leading to the activation of pro-apoptotic factors and the inhibition of anti-apoptotic proteins. This compound also enhances the production of reactive oxygen species, which can induce oxidative stress in cancer cells. Additionally, Ginsenoside Re may alter gene expression profiles, further contributing to its antitumor effects.

Epirubicin Hydrochloride

56390-09-1sc-203041
sc-203041A
sc-203041B
5 mg
25 mg
100 mg
$150.00
$286.00
$539.00
2
(1)

Epirubicin Hydrochloride functions as an antitumor agent by intercalating into DNA, disrupting the replication process and inhibiting topoisomerase II activity. This interference leads to the formation of DNA adducts, triggering cellular stress responses. The compound also generates reactive oxygen species, which can damage cellular components and promote apoptosis. Its unique structure allows for selective binding to tumor cells, enhancing its efficacy in targeting malignant tissues.

Idarubicin Hydrochloride

57852-57-0sc-204774
sc-204774A
sc-204774B
sc-204774C
1 mg
5 mg
10 mg
50 mg
$72.00
$170.00
$269.00
$740.00
2
(2)

Idarubicin Hydrochloride exhibits antitumor properties through its ability to form stable complexes with DNA, effectively altering the helical structure and preventing proper transcription. This compound also interacts with various cellular enzymes, modulating their activity and disrupting metabolic pathways essential for cell survival. Additionally, its lipophilic nature facilitates cellular uptake, enhancing its interaction with intracellular targets and promoting cytotoxic effects.

Ciglitazone

74772-77-3sc-200902
sc-200902A
5 mg
25 mg
$102.00
$420.00
10
(1)

Ciglitazone demonstrates antitumor activity by selectively activating peroxisome proliferator-activated receptors (PPARs), which modulate gene expression linked to cell proliferation and apoptosis. Its unique ability to influence metabolic pathways alters energy homeostasis within tumor cells, leading to reduced growth. Furthermore, Ciglitazone's interactions with specific signaling cascades can enhance oxidative stress, contributing to its cytotoxic effects on malignant cells.

Ansatrienin B

82189-04-6sc-202954
1 mg
$409.00
(0)

Ansatrienin B exhibits antitumor properties through its ability to disrupt cellular signaling pathways, particularly by inhibiting key enzymes involved in tumor metabolism. This compound interacts with specific protein targets, leading to altered cell cycle regulation and enhanced apoptosis in cancer cells. Its unique structural features allow for selective binding, which can modulate the activity of growth factors and cytokines, ultimately impairing tumor progression and survival.

Rebeccamycin

93908-02-2sc-202309
sc-202309A
250 µg
1 mg
$153.00
$306.00
(0)

Rebeccamycin demonstrates antitumor activity by interfering with DNA topoisomerase I, crucial for DNA replication and transcription. This compound forms stable complexes with the enzyme, preventing the relaxation of supercoiled DNA, which is essential for cell division. Its unique chromophore structure enhances binding affinity, leading to effective disruption of tumor cell proliferation. Additionally, Rebeccamycin's ability to induce oxidative stress contributes to its cytotoxic effects on malignant cells.

CI 994

112522-64-2sc-205245
sc-205245A
10 mg
50 mg
$97.00
$525.00
1
(2)

CI 994 exhibits antitumor properties through its role as a selective inhibitor of histone deacetylases (HDACs), which are vital for regulating gene expression. By altering the acetylation status of histones, CI 994 promotes a more open chromatin structure, facilitating transcription of tumor suppressor genes. This compound's unique interaction with the HDAC enzyme alters cellular signaling pathways, leading to cell cycle arrest and apoptosis in cancer cells. Its distinct mechanism highlights the importance of epigenetic modulation in cancer therapy.

Dolastatin 15

123884-00-4sc-201449
1 mg
$299.00
4
(1)

Dolastatin 15 is a potent antitumor agent derived from marine sources, known for its ability to disrupt microtubule dynamics. It binds to tubulin, inhibiting polymerization and leading to cell cycle arrest. This compound's unique interaction with the mitotic spindle apparatus triggers apoptosis in rapidly dividing cells. By interfering with cellular transport mechanisms and signaling pathways, Dolastatin 15 showcases a distinctive approach to targeting cancer cell proliferation.