Date published: 2025-10-18

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Amine-Reactive

Santa Cruz Biotechnology now offers a broad range of Amine-reactive compounds for use in various applications. Amine-reactive compounds are fundamental tools in scientific research, particularly in the fields of biochemistry and molecular biology. These chemicals are designed to selectively react with amine groups, which are prevalent in amino acids and proteins, enabling targeted modifications that are crucial for studying protein structure, function, and interactions. Amine-reactive compounds are extensively utilized in labeling or crosslinking studies, where they facilitate the attachment of fluorescent tags or other markers to proteins for visualization and identification purposes. This makes them invaluable in proteomics, where understanding protein interactions, localization, and dynamics within cells is essential. Additionally, these compounds play a pivotal role in material science for surface modification of polymers and creation of biocompatible materials. In analytical chemistry, amine-reactive dyes and probes are critical for developing assays that can detect and quantify biological molecules, significantly impacting diagnostics and biochemical research. Beyond practical applications, the study of amine-reactive chemistry helps elucidate reaction mechanisms and improve synthetic methodologies, furthering the chemical sciences. The breadth of applications across multiple disciplines underscores the versatility and importance of amine-reactive compounds in advancing scientific knowledge and technology. View detailed information on our available Amine-reactive compounds by clicking on the product name.

Items 21 to 30 of 66 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Chromeo™ P503

sc-364758
1 mg
$423.00
(0)

Chromeo™ P503 stands out as an amine due to its exceptional ability to engage in nucleophilic substitution reactions, particularly with electrophiles. Its unique molecular architecture promotes strong hydrogen bonding interactions, enhancing its reactivity profile. The compound exhibits favorable solubility characteristics, allowing for efficient diffusion in various media. Additionally, its distinct electronic properties facilitate rapid reaction kinetics, making it a versatile candidate for diverse synthetic pathways.

Tetramethylrhodamine-5-isothiocyanate

80724-19-2sc-215960
5 mg
$216.00
2
(0)

Tetramethylrhodamine-5-isothiocyanate, as an amine, showcases remarkable reactivity through its isothiocyanate functional group, which readily forms thiourea derivatives upon reaction with amines. This compound exhibits strong fluorescence properties, enabling it to serve as a powerful probe in various chemical environments. Its unique steric configuration enhances selectivity in reactions, while its robust stability under diverse conditions allows for prolonged interaction with target molecules, facilitating intricate molecular studies.

Dansyl Chloride

605-65-2sc-359844
1 g
$67.00
2
(0)

Dansyl Chloride, as an amine-reactive compound, features a sulfonamide moiety that enables it to form stable sulfonamide bonds with primary and secondary amines. This reactivity is characterized by a rapid acylation process, leading to the formation of fluorescent dansyl derivatives. The compound's distinct electronic properties impart a strong fluorescence, making it an effective marker in various analytical techniques. Its hydrophobic nature enhances solubility in organic solvents, promoting diverse applications in chemical synthesis and labeling.

Fluorescein 6-Isothiocyanate, Isomer 2, 95%

18861-78-4sc-218501
100 mg
$230.00
(0)

Fluorescein 6-Isothiocyanate, Isomer 2, exhibits remarkable reactivity towards amines, facilitating the formation of thiourea linkages. This compound's unique isothiocyanate group allows for selective labeling, enabling precise tracking of biomolecules. Its strong fluorescence is attributed to the conjugated system, which enhances light absorption and emission. Additionally, the compound's solubility in polar solvents aids in various chemical interactions, making it a versatile tool in bioconjugation and imaging studies.

4-Fluoro-7-nitrobenzofurazan

29270-56-2sc-214238
sc-214238A
sc-214238B
5 mg
25 mg
50 mg
$200.00
$588.00
$982.00
(0)

4-Fluoro-7-nitrobenzofurazan is a highly reactive compound that engages in nucleophilic substitution reactions with amines, leading to the formation of stable adducts. Its nitro and fluoro substituents enhance electron-withdrawing properties, promoting electrophilic attack. The compound exhibits strong fluorescence due to its unique conjugated structure, which facilitates efficient energy transfer. Additionally, its solubility in organic solvents allows for diverse applications in chemical synthesis and material science.

7-(Diethylamino)coumarin-3-carboxylic acid

50995-74-9sc-210586
100 mg
$149.00
(0)

7-(Diethylamino)coumarin-3-carboxylic acid is a versatile compound characterized by its strong electron-donating diethylamino group, which enhances its reactivity in various chemical environments. This compound exhibits notable fluorescence, attributed to its extended π-conjugation, making it useful in photophysical studies. Its carboxylic acid functionality allows for hydrogen bonding interactions, influencing solubility and reactivity in polar solvents, and facilitating complex formation with metal ions.

Tetramethylrhodamine isothiocyanate Isomer R

80724-20-5sc-215957
sc-215957A
5 mg
10 mg
$188.00
$325.00
(0)

Tetramethylrhodamine isothiocyanate Isomer R is a highly reactive dye known for its robust electrophilic properties, particularly in nucleophilic substitution reactions. The isothiocyanate group enables selective labeling of amines, facilitating the formation of stable thiourea linkages. Its intense fluorescence arises from a rigid structure that minimizes non-radiative decay, making it ideal for tracking molecular interactions. Additionally, its hydrophobic characteristics influence partitioning in biological systems, enhancing its utility in various analytical applications.

Sulforhodamine 101 acid chloride

82354-19-6sc-215930
sc-215930A
10 mg
25 mg
$173.00
$438.00
(1)

Sulforhodamine 101 acid chloride is a potent electrophile, exhibiting a strong tendency to engage in acylation reactions with amines. Its unique structure allows for rapid formation of stable amide bonds, driven by the release of hydrochloric acid. The compound's high reactivity is complemented by its ability to form conjugates that exhibit distinct spectral properties, enhancing detection capabilities. Additionally, its solubility in organic solvents facilitates diverse synthetic pathways, making it a versatile reagent in chemical transformations.

7-Amino-4-methyl-3-coumarinylacetic acid

106562-32-7sc-214395
sc-214395A
100 mg
500 mg
$75.00
$206.00
(0)

7-Amino-4-methyl-3-coumarinylacetic acid is characterized by its ability to participate in nucleophilic acyl substitution reactions, showcasing a remarkable reactivity profile. The presence of the amino group enhances its interaction with electrophiles, promoting the formation of stable amide linkages. Its unique coumarin structure contributes to distinct photophysical properties, allowing for effective fluorescence modulation. This compound's solubility in various solvents further supports its utility in diverse synthetic applications.

5(6)-Carboxy-X-rhodamine N-succinimidyl ester

114616-32-9sc-210422
25 mg
$210.00
(0)

5(6)-Carboxy-X-rhodamine N-succinimidyl ester exhibits a high reactivity towards amines, facilitating the formation of stable amide bonds through its electrophilic N-succinimidyl ester moiety. This compound is notable for its intense fluorescence, which is influenced by its rhodamine core, allowing for effective signal amplification in various assays. Its ability to undergo rapid conjugation reactions makes it a versatile tool in bioconjugation strategies, enhancing molecular interactions in complex systems.