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7-Amino-4-methyl-3-coumarinylacetic acid (CAS 106562-32-7)

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Alternate Names:
2H-1-Benzopyran-3-acetic acid; AMCA-H
Application:
7-Amino-4-methyl-3-coumarinylacetic acid is a blue fluorophore useful for immunofluorescence and peptide labeling
CAS Number:
106562-32-7
Purity:
≥90%
Molecular Weight:
233.22
Molecular Formula:
C12H11NO4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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7-Amino-4-methyl-3-coumarinylacetic acid is a blue fluorophore useful for immunofluorescence and peptide labeling.


7-Amino-4-methyl-3-coumarinylacetic acid (CAS 106562-32-7) References

  1. Synthesis and fluorescent labeling of beta-amyloid peptides.  |  Fülöp, L., et al. 2001. J Pept Sci. 7: 397-401. PMID: 11548055
  2. A spectrophotometric method for determination of fluorophore-to-protein ratios in conjugates of the blue fluorophore 7-amino-4-methylcoumarin-3-acetic acid (AMCA).  |  Wessendorf, MW., et al. 1990. J Histochem Cytochem. 38: 87-94. PMID: 1688452
  3. Synthesis of Abeta[1-42] and its derivatives with improved efficiency.  |  Zarándi, M., et al. 2007. J Pept Sci. 13: 94-9. PMID: 17103463
  4. Synthesis and characterization of a series of highly fluorogenic substrates for glutathione transferases, a general strategy.  |  Zhang, J., et al. 2011. J Am Chem Soc. 133: 14109-19. PMID: 21786801
  5. Analysis of fluorescence quenching of coumarin derivatives by 4-hydroxy-TEMPO in aqueous solution.  |  Żamojć, K., et al. 2014. J Fluoresc. 24: 713-8. PMID: 24337873
  6. A blue fluorescent labeling technique utilizing micro- and nanoparticles for tracking in LIVE/DEAD® stained pathogenic biofilms of Staphylococcus aureus and Burkholderia cepacia.  |  Klinger-Strobel, M., et al. 2016. Int J Nanomedicine. 11: 575-83. PMID: 26917959
  7. A combined spectroscopic and TDDFT investigation of the solute-solvent interactions of two coumarin derivatives.  |  Shivraj, ., et al. 2017. Luminescence. 32: 1328-1338. PMID: 28581184
  8. A continuous fluorescence assay for simple quantification of bile salt hydrolase activity in the gut microbiome.  |  Brandvold, KR., et al. 2019. Sci Rep. 9: 1359. PMID: 30718677
  9. Effects of surface treatments on trapping with DC insulator-based dielectrophoresis.  |  Crowther, CV., et al. 2019. Analyst. 144: 7478-7488. PMID: 31720589
  10. Melittin Tryptophan Substitution with a Fluorescent Amino Acid Reveals the Structural Basis of Selective Antitumor Effect and Subcellular Localization in Tumor Cells.  |  Lv, Y., et al. 2022. Toxins (Basel). 14: PMID: 35878166

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

7-Amino-4-methyl-3-coumarinylacetic acid, 100 mg

sc-214395
100 mg
$75.00

7-Amino-4-methyl-3-coumarinylacetic acid, 500 mg

sc-214395A
500 mg
$206.00