Date published: 2026-4-24

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α-dystroglycan Antibodies

Santa Cruz Biotechnology delivers a wide array of α-dystroglycan monoclonal antibodies for research applications. α-dystroglycan Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). α-Dystroglycan is a vital component of the dystrophin-glycoprotein complex, playing a key role in linking the extracellular matrix to the cytoskeleton of muscle cells. Muscle integrity and function depend on α-dystroglycan, which is essential for the development and maintenance of skeletal muscle and the central nervous system. Research has shown that α-dystroglycan dysregulation is associated with various muscular dystrophies and other diseases, highlighting its significance in both normal physiology and pathological conditions. Scientists worldwide utilize α-dystroglycan monoclonal antibodies to investigate cellular signaling pathways and molecular mechanisms. Understanding α-dystroglycan's role in disease progression helps identify potential therapeutic targets and develop new treatment strategies. Research with α-dystroglycan monoclonal antibodies from Santa Cruz Biotechnology continues to advance scientific knowledge and contribute to breakthrough discoveries in muscle biology and neuroscience.

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α-dystroglycan Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

α-dystroglycan Antibody (IIH6)

sc-53987mouse IgM κFL (rabbit)WB, IP, IF, IHC(P)m, r, h, rabbit and canine
32
(8)

α-dystroglycan Antibody (VIA41)

sc-53986mouse IgG1 κFL (rabbit)WB, IPm, r, h, bovine, rabbit and canine
6
(3)

α-dystroglycan Antibody (2237E2D1)

sc-65628mouse IgG2b κ(bovine)WB, IPbovine

new

(1)

α-dystroglycan Antibody (D-3)

sc-271589mouse IgG2a κ30-329 (h)WB, IP, IF, ELISAm, r, h
1
(1)

α-dystroglycan Antibody (IIH6C4)

sc-73586mouse IgM κFL (rabbit)WB, IPm, r, h and rabbit
4
(2)

α-dystroglycan Antibody (2238E2D2)

sc-65629mouse IgG2b κ(bovine)WBm, r, h, bovine and rabbit

new

(1)

α-dystroglycan CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

α-dystroglycan CRISPR/Cas9 KO Plasmid (m)

sc-419941mGene KnockoutGFP0
(0)

α-dystroglycan HDR Plasmid (m)

sc-419941-HDRmHomology Directed RepairPuromycin0
(0)

α/β-dystroglycan CRISPR/Cas9 KO Plasmid (h)

sc-417547hGene KnockoutGFP0
(0)

α/β-dystroglycan HDR Plasmid (h)

sc-417547-HDRhHomology Directed RepairPuromycin0
(0)

α/β-dystroglycan Double Nickase Plasmid (h)

sc-417547-NIChGene KnockoutPuromycin0
(0)

α/β-dystroglycan Double Nickase Plasmid (h2)

sc-417547-NIC-2hGene KnockoutPuromycin0
(0)

α-dystroglycan siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

α-dystroglycan shRNA Plasmid (h)

sc-43488-SHhGene SilencingPuromycin
2
(0)

α-dystroglycan shRNA (h) Lentiviral Particles

sc-43488-VhGene SilencingPuromycin
2
(0)

α-dystroglycan shRNA Plasmid (m)

sc-43489-SHmGene SilencingPuromycin0
(0)

α-dystroglycan shRNA (m) Lentiviral Particles

sc-43489-VmGene SilencingPuromycin0
(0)

α/β-dystroglycan siRNA (h)

sc-43488hGene SilencingN/A
2
(0)

α/β-dystroglycan siRNA (m)

sc-43489mGene SilencingN/A0
(0)