Date published: 2025-11-21

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ADAR1 Antibodies

Santa Cruz Biotechnology provides a broad selection of ADAR1 monoclonal antibodies for research focused on understanding RNA editing mechanisms. ADAR1 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). ADAR1, or adenosine deaminase acting on RNA 1, plays a vital role in editing RNA molecules, significantly impacting gene expression and cellular stress responses. RNA editing by ADAR1 is particularly significant during viral infections and autoimmune conditions, where it helps modulate immune responses by editing viral RNA and preventing harmful pathway activation. Research has shown that ADAR1 dysfunction can lead to various pathological conditions, making it an important target for therapeutic development. Understanding ADAR1's molecular mechanisms and cellular functions continues to reveal new insights into RNA biology and disease processes. Investigating ADAR1's role in different biological pathways helps advance our knowledge of RNA editing mechanisms and their impact on human health. ADAR1 research has opened new avenues for developing targeted therapies for various diseases, including autoimmune disorders and viral infections. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of RNA editing mechanisms and their therapeutic applications.

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ADAR1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

ADAR1 Antibody (D-8)

sc-271854mouse IgG1 λ1051-1226 (h)WB, IP, IF, IHC(P), ELISAh
21
(11)

ADAR1 Antibody (15.8.6)

sc-73408mouse IgG1 κ440-826 (h)WB, IP, IF, IHC(P)m, r, h
88
(17)

ADAR1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ADAR1 CRISPR/Cas9 KO Plasmid (h)

sc-401611hGene KnockoutGFP
1
(0)

ADAR1 HDR Plasmid (h)

sc-401611-HDRhHomology Directed RepairPuromycin
1
(0)

ADAR1 Double Nickase Plasmid (h)

sc-401611-NIChGene KnockoutPuromycin
1
(0)

ADAR1 Double Nickase Plasmid (h2)

sc-401611-NIC-2hGene KnockoutPuromycin
1
(0)

ADAR1 CRISPR/Cas9 KO Plasmid (m)

sc-425147mGene KnockoutGFP0
(0)

ADAR1 HDR Plasmid (m)

sc-425147-HDRmHomology Directed RepairPuromycin0
(0)

ADAR1 Double Nickase Plasmid (m)

sc-425147-NICmGene KnockoutPuromycin0
(0)

ADAR1 Double Nickase Plasmid (m2)

sc-425147-NIC-2mGene KnockoutPuromycin0
(0)

ADAR1 CRISPR Activation Products

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ADAR1 CRISPR Activation Plasmid (h)

sc-401611-ACThGene ActivationPuro, Blast, Hygro
1
(0)

ADAR1 CRISPR Activation Plasmid (h2)

sc-401611-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

ADAR1 Lentiviral Activation Particles (h)

sc-401611-LAChGene ActivationPuro, Blast, Hygro
1
(0)

ADAR1 Lentiviral Activation Particles (h2)

sc-401611-LAC-2hGene ActivationPuro, Blast, Hygro
1
(0)

ADAR1 CRISPR Activation Plasmid (m)

sc-425147-ACTmGene ActivationPuro, Blast, Hygro0
(0)

ADAR1 CRISPR Activation Plasmid (m2)

sc-425147-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

ADAR1 Lentiviral Activation Particles (m)

sc-425147-LACmGene ActivationPuro, Blast, Hygro0
(0)

ADAR1 Lentiviral Activation Particles (m2)

sc-425147-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

ADAR1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ADAR1 siRNA (h)

sc-37657hGene SilencingN/A
5
(0)

ADAR1 shRNA Plasmid (h)

sc-37657-SHhGene SilencingPuromycin
5
(0)

ADAR1 shRNA (h) Lentiviral Particles

sc-37657-VhGene SilencingPuromycin
5
(0)

ADAR1 siRNA (m)

sc-37658mGene SilencingN/A
2
(0)

ADAR1 shRNA Plasmid (m)

sc-37658-SHmGene SilencingPuromycin
2
(0)

ADAR1 shRNA (m) Lentiviral Particles

sc-37658-VmGene SilencingPuromycin
2
(0)