ABCB8 Activators
ABCB8 Activators encompasses a group of molecules that have shown the ability to modulate the activity of the ATP-binding cassette sub-family B member 8 (ABCB8) protein within cellular systems. ABCB8 is a mitochondrial protein integral to maintaining mitochondrial function and health, primarily by regulating the transport of various molecules across the inner mitochondrial membrane. The role of ABCB8 in cellular physiology is crucial as it impacts the efficient functioning of mitochondria, the cell's powerhouse responsible for energy production and various metabolic processes. ABCB8 Activators have been investigated for their potential to enhance the transport functions of ABCB8, thus contributing to the overall well-being of mitochondria.
These compounds may operate through different mechanisms, including promoting the expression or activity of ABCB8, optimizing its interaction with other mitochondrial proteins, or influencing the cellular signaling pathways connected to mitochondrial function. While the precise modes of action of ABCB8 Activators may vary, their common goal is to enhance the proper transport of molecules, such as ions, metabolites, or cofactors, across the inner mitochondrial membrane. By doing so, these compounds may indirectly impact the energy production, metabolic processes, and overall cellular health, as the proper functioning of mitochondria is intricately linked to these fundamental cellular activities.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Coenzyme Q10 | 303-98-0 | sc-205262 sc-205262A | 1 g 5 g | $71.00 $184.00 | 1 | |
Coenzyme Q10 directly engages with the mitochondrial electron transport chain, indirectly stimulating ABCB8 by contributing to efficient electron transport and overall mitochondrial health. | ||||||
Melatonin | 73-31-4 | sc-207848 sc-207848A sc-207848B sc-207848C sc-207848D sc-207848E | 1 g 5 g 25 g 100 g 250 g 1 kg | $65.00 $73.00 $218.00 $697.00 $1196.00 $3574.00 | 16 | |
Melatonin indirectly stimulates ABCB8 by potentially protecting mitochondrial function, vital for the energy supply within cells, and enhancing ABCB8's role in mitochondrial homeostasis. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol indirectly promotes ABCB8 by its antioxidant and anti-inflammatory properties, which help maintain mitochondrial function and mitigate oxidative stress within mitochondria. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $110.00 $150.00 $220.00 $300.00 $600.00 | 4 | |
NMN serves as a precursor to NAD+ and indirectly activates ABCB8 by promoting cellular NAD+ levels crucial for mitochondrial health and function. | ||||||
Creatine, anhydrous | 57-00-1 | sc-214774 sc-214774A | 10 mg 50 g | $28.00 $79.00 | 2 | |
Creatine indirectly stimulates ABCB8 by bolstering the ATP-PCr energy system, which enhances cellular energy supply and indirectly benefits mitochondrial function. | ||||||
L-Carnitine | 541-15-1 | sc-205727 sc-205727A sc-205727B sc-205727C | 1 g 5 g 100 g 250 g | $23.00 $34.00 $79.00 $179.00 | 3 | |
L-Carnitine indirectly encourages ABCB8 by facilitating the transport of fatty acids into mitochondria, a process that activates mitochondrial fatty acid metabolism and cellular energy production. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
Alpha-lipoic acid indirectly activates ABCB8 by acting as an antioxidant, reducing oxidative stress, and promoting mitochondrial health, potentially enhancing ABCB8's role in maintaining mitochondrial function. | ||||||
2,4-Dinitrophenol, wetted | 51-28-5 | sc-238345 | 250 mg | $59.00 | 2 | |
DNP indirectly activates ABCB8 by uncoupling mitochondrial respiration, which can lead to increased energy dissipation as heat. This can impact mitochondrial function and ABCB8 activity but should be used cautiously due to its toxicity. | ||||||