AARD Activators
AARD, or Alanine And Arginine Rich Domain Containing Protein, is a protein that has been identified through genomic sequencing efforts but is not well-characterized in the literature. As such, detailed functional information about AARD is limited. The name suggests that this protein contains a rich presence of the amino acids alanine and arginine, which might indicate a role in protein-protein interactions or in the regulation of enzymatic activity, as these amino acids are often found in active or binding sites of proteins.
The presence of specific domains, like a rich distribution of alanine and arginine, can sometimes hint at a protein's function. For instance, arginine-rich motifs are recognized for their ability to bind to nucleic acids and are often found in RNA-binding proteins, which suggests that AARD may play a role in RNA metabolism or regulation of gene expression. Alanine-rich regions, on the other hand, could contribute to the formation of alpha-helix structures, which are common in fibrous proteins and may be involved in the formation of protein scaffolds within cells
Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which can phosphorylate serine and threonine residues in proteins, potentially enhancing the activity of the alanine and arginine rich domain containing protein. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Forskolin elevates cAMP, which activates PKA. PKA phosphorylation can lead to enhanced activity of proteins with alanine and arginine rich domains. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 increases intracellular calcium levels, which can activate calcium-dependent proteins and potentially enhance the activity of the alanine and arginine rich domain containing protein. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin is a calcium ionophore that raises intracellular calcium levels, potentially activating proteins that are modulated by calcium signaling. | ||||||
8-Bromoadenosine 3′,5′-cyclic monophosphate | 23583-48-4 | sc-217493B sc-217493 sc-217493A sc-217493C sc-217493D | 25 mg 50 mg 100 mg 250 mg 500 mg | $106.00 $166.00 $289.00 $550.00 $819.00 | 2 | |
8-Br-cAMP is a cAMP analog that activates PKA, which could enhance phosphorylation of the alanine and arginine rich domain containing protein. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 inhibits PI3K, altering downstream signaling which can lead to activation of proteins involved in related signaling pathways. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
This lipid signaling molecule activates G protein-coupled receptors, potentially influencing the activity of various proteins including those with alanine and arginine rich domains. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is a kinase inhibitor that may shift the balance of cell signaling towards pathways that activate proteins with specific amino acid-rich domains. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 inhibits MEK1/2, which could modulate signaling pathways and indirectly enhance the activity of certain proteins. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
This compound inhibits p38 MAPK, potentially affecting pathways that activate proteins with rich domains of specific amino acids. | ||||||