AARD, or Alanine And Arginine Rich Domain Containing Protein, is a protein that has been identified through genomic sequencing efforts but is not well-characterized in the literature. As such, detailed functional information about AARD is limited. The name suggests that this protein contains a rich presence of the amino acids alanine and arginine, which might indicate a role in protein-protein interactions or in the regulation of enzymatic activity, as these amino acids are often found in active or binding sites of proteins.
The presence of specific domains, like a rich distribution of alanine and arginine, can sometimes hint at a protein's function. For instance, arginine-rich motifs are recognized for their ability to bind to nucleic acids and are often found in RNA-binding proteins, which suggests that AARD may play a role in RNA metabolism or regulation of gene expression. Alanine-rich regions, on the other hand, could contribute to the formation of alpha-helix structures, which are common in fibrous proteins and may be involved in the formation of protein scaffolds within cells
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin disrupts calcium homeostasis, which can lead to the activation of calcium-dependent proteins and pathways. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A sc-24000B sc-24000C | 10 µg 100 µg 500 µg 1 mg | $160.00 $750.00 $1400.00 $3000.00 | 59 | |
As an inhibitor of protein phosphatases, Calyculin A may increase phosphorylation levels of proteins, possibly enhancing the activity of those with alanine and arginine rich domains. |