NOS Inhibitors

Santa Cruz Biotechnology now offers a broad range of NOS Inhibitors. Nitric oxide (NO) has a broad range of biological activities including cell signaling pathways in phylogenetically diverse species. Nitric oxide synthases (NOSs), the enzymes responsible for synthesis of NO, contain an N-terminal oxygenase domain and a C-terminal reductase domain. NOS activity requires homodimerization as well as three cosubstrates (L-arginine, NADPH and O2) and five cofactors or prosthetic groups (FAD, FMN, calmodulin, tetrahydrobiopterin and heme). NOS Inhibitors offered by Santa Cruz inhibit NOS and, in some cases, other cell signaling and nitric oxide synthesis related proteins. View detailed NOS Inhibitor specifications, including NOS Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
1,5-Isoquinolinediol
1,5-Isoquinolinediol is an inhibitor of PARP, NOS-2, and PARS
5154-02-9 sc-200127
sc-200127A
20 mg
100 mg
$57.00
$237.00
5
(1)
NG,NG-Dimethylarginine Dihydrochloride
NG,NG-Dimethylarginine Dihydrochloride is a cell-permeable, reversible inhibitor of nitric oxide synthase
220805-22-1 sc-208093
50 mg
$210.00
0
(1)
Ebselen
Ebselen is a cysteine modifier that inhibits 5-LO, 15-LO, Cox, NADPH, and NADPH oxidase
60940-34-3 sc-200740B
sc-200740
sc-200740A
1 mg
25 mg
100 mg
$26.00
$125.00
$435.00
5
(1)
p-Nitroblue tetrazolium chloride
p-Nitroblue tetrazolium chloride is a competitive inhibitor of NOS
298-83-9 sc-296003
sc-296003A
250 mg
5 g
$77.00
$253.00
1
(1)
Aminoguanidine bicarbonate
CAS: 2582-30-1. MW: 136.11. MF: CH6N4•H2CO3.
2582-30-1 sc-202460
sc-202460A
100 g
500 g
$20.00
$49.00
0
(0)
Bromocriptine mesylate
Bromocriptine mesylate is a selective D2 and D3 dopamine receptor agonist and NOS1 inhibitor
22260-51-1 sc-200395
sc-200395A
sc-200395B
100 mg
500 mg
1 g
$86.00
$344.00
$520.00
3
(1)
Methylene blue trihydrate
Methylene blue trihydrate is an inhibitor of cGMP-mediated processes and guanylyl cyclase, a useful stain, and a redox indicator
7220-79-3 sc-203744
sc-203744A
5 g
25 g
$30.00
$60.00
3
(1)
Paroxetine HCl
Paroxetine HCl is a highly potent and selective serotonin (5-HT) uptake inhibitor
78246-49-8 sc-201141
sc-201141A
20 mg
100 mg
$92.00
$360.00
2
(1)
NG, NG-Dimethyl-L-arginine di(p-hydroxyazobenzene-pprime-sulfonate)
NG, NG-Dimethyl-L-arginine di(p-hydroxyazobenzene-p′-sulfonate) is a NOS inhibitor
sc-224167
sc-224167A
25 mg
25 mg
$41.00
$0.00
1
(0)
Costunolide
Costunolide is a sequiterpene lactone that inhibits telomerase
553-21-9 sc-203555
sc-203555A
1 mg
10 mg
$79.00
$165.00
0
(0)
Elaiophylin
Elaiophylin is a macrolide antibiotic with immunosuppresive activity
37318-06-2 sc-202147
sc-202147A
sc-202147B
sc-202147C
sc-202147D
sc-202147E
1 mg
5 mg
10 mg
25 mg
50 mg
100 mg
$181.00
$425.00
$527.00
$1,040.00
$1,900.00
$3,347.00
1
(1)
Melatonin-d4
Melatonin-d4 is an antioxidant and indoleamine neurohormone postulated to mediate photoperiodicity in mammals.
66521-38-8 sc-207849
sc-207849B
sc-207849A
2.5 mg
5 mg
10 mg
$390.00
$440.00
$840.00
4
(2)
S-Isopropyl-ITU hydrobromide
S-Isopropyl-ITU hydrobromide is an inhibitor of NOS
4269-97-0 sc-222276
sc-222276A
10 mg
50 mg
$20.00
$30.00
0
(0)
Arcaine sulfate
Arcaine sulfate is a novel and potent antagonist of the polyamine site on the NMDA receptor
14923-17-2 sc-200475
sc-200475A
20 mg
50 mg
$70.00
$74.00
0
(0)
NG, NprimeG-Dimethyl-L-arginine di(p-hydroxyazobenzene-pprime-sulfonate)
NG, N′G-Dimethyl-L-arginine di(p-hydroxyazobenzene-p′-sulfonate) is a reversible inhibitor of nitric oxide synthesis
102783-24-4 sc-202235
sc-202235A
5 mg
25 mg
$67.00
$231.00
0
(0)
1400 W
1400 W is a highly potent and selective inhibitor of inducible NOS2 (iNOS)
214358-33-5 sc-3564
sc-3564A
5 mg
25 mg
$55.00
$157.00
8
(1)
2-Iminobiotin
2-Iminobiotin is a reversible inhibitor of mouse NOS2 and rat NOS1
13395-35-2 sc-202403
sc-202403A
sc-202403B
sc-202403C
sc-202403D
sc-202403E
sc-202403F
10 mg
50 mg
100 mg
1 g
5 g
10 g
50 g
$30.00
$65.00
$138.00
$1,163.00
$4,628.00
$6,800.00
$20,990.00
0
(0)
L-NIL dihydrochloride
L-NIL dihydrochloride is a selective inhibitor of NOS2 over NOS1
159190-45-1 sc-205362
sc-205362A
5 mg
10 mg
$25.00
$39.00
1
(0)
Camptothecin
Camptothecin is a reversible Mitochondrial Topo I inhibitor shown to exhibit antitumor activity
7689-03-4 sc-200871
sc-200871B
sc-200871A
50 mg
100 mg
250 mg
$46.00
$80.00
$168.00
19
(2)
L-NG-Nitroarginine Methyl Ester (L-NAME)
L-NG-Nitroarginine Methyl Ester (L-NAME) is a precursor to NOS inhibitor, L-NNA - requires bioactivation to become a fully functional inhibitor
51298-62-5 sc-200333
sc-200333A
sc-200333B
1 g
5 g
25 g
$36.00
$93.00
$305.00
39
(1)
L-NG-Monomethylarginine, Acetate Salt (L-NMMA)
L-NG-Monomethylarginine, Acetate Salt (L-NMMA) is an L-arginine analogue inhibitor of Ca2+-dependent NOS3 (endothelial NOS)
53308-83-1 sc-200739
sc-200739A
sc-200739B
sc-200739C
25 mg
100 mg
1 g
100 g
$62.00
$210.00
$640.00
$38,800.00
3
(1)
Chlorpromazine, Hydrochloride
Chlorpromazine, Hydrochloride is an inhibitor of PDE, D2DR, NOS1, and PLA2
69-09-0 sc-202537
sc-202537A
sc-202537B
sc-202537C
sc-202537D
500 mg
5 g
25 g
100 g
250 g
$32.00
$48.00
$140.00
$480.00
$1,060.00
5
(1)
Curcumin
Curcumin is a yellow-orange dye, NOS2 regulator, and inhibitor of NF-κB, 5-LO, Cox-2, COP9, and p300/CBP.
458-37-7 sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$19.00
$38.00
$60.00
$110.00
$220.00
$835.00
$1,920.00
38
(2)
N-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-Nprime-nitroguanidine tris(trifluoroacetate) salt
N-[(4S)-4-amino-5-[(2-aminoethyl)amino]pentyl]-N′-nitroguanidine tris(trifluoroacetate) salt is a cell-permeable, potent and highly selective inhibitor of NOS1 (nNOS)
357965-99-2 sc-215427
sc-215427A
5 mg
25 mg
$140.00
$700.00
3
(2)
Zinc Protoporphyrin-9
Zinc Protoporphyrin-9 is a potent, selective inhibitor of heme oxygenase, GCS, NOS1, NOS2, and NOS3.
15442-64-5 sc-200329
sc-200329A
25 mg
100 mg
$65.00
$195.00
30
(1)
D-NG-Monomethylarginine (D-NMMA)
D-NG-Monomethylarginine (D-NMMA) is a negative control for L-NMMA
137694-75-8 sc-200332
5 mg
$54.00
10
(1)
D-NG-Nitroarginine Methyl Ester hydrochloride
D-NG-Nitroarginine Methyl Ester hydrochloride is inactive stereoisomer of L-NAME NOS inhibitor
50912-92-0 sc-200335
sc-200335A
250 mg
1 g
$24.00
$114.00
2
(1)
N(5)-(1-Iminoethyl)-L-ornithine HCl (L-NIO)
N(5)-(1-Iminoethyl)-L-ornithine HCl (L-NIO) is an inhibitor of NOS3
150403-88-6 sc-200343
sc-200343A
10 mg
100 mg
$177.00
$1,305.00
4
(1)
3-Bromo-7-nitroindazole
3-Bromo-7-nitroindazole is a selective inhibitor of NOS1 and NOS3
74209-34-0 sc-200347
sc-200347A
5 mg
25 mg
$20.00
$26.00
1
(1)
S-Ethylisothiourea HBr
S-Ethylisothiourea HBr is a highly potent L-Arginine competitive inhibitor of NOS2
1071-37-0 sc-200351
50 mg
$20.00
2
(0)
Diphenyleneiodonium chloride
Diphenyleneiodonium chloride is an inhibitor of NOS2 (iNOS), NOS3 (eNOS), and neutrophil NADPH oxidase.
4673-26-1 sc-202584E
sc-202584
sc-202584D
sc-202584A
sc-202584B
sc-202584C
10 mg
25 mg
50 mg
100 mg
250 mg
500 mg
$140.00
$125.00
$260.00
$384.00
$902.00
$1,761.00
23
(1)
TRIM
TRIM is a NOS1 (nNOS) and NOS2 (iNOS) inhibitor
25371-96-4 sc-200353
sc-200353A
100 mg
500 mg
$95.00
$315.00
0
(0)
Gallotannin
Gallotannin is an inhibitor of NOS3 and a weak inhibitor of NOS2 and NOS1
1401-55-4 sc-202619
sc-202619A
sc-202619B
sc-202619C
sc-202619D
sc-202619E
sc-202619F
1 g
10 g
100 g
250 g
1 kg
2.5 kg
5 kg
$20.00
$30.00
$60.00
$70.00
$220.00
$510.00
$940.00
11
(1)
(−)-Epigallocatechin Gallate
(−)-Epigallocatechin Gallate is a strong polyphenol catechin antioxidant and inhibitor of Bcl-2 and NOS2.
989-51-5 sc-200802
sc-200802A
sc-200802B
sc-200802C
sc-200802D
sc-200802E
10 mg
50 mg
100 mg
500 mg
1 g
10 g
$31.00
$60.00
$112.00
$224.00
$500.00
$1,200.00
11
(1)
Melatonin
Melatonin is a neurohormone that upregulates antioxidant enzymes and inhibits rat NOS1
73-31-4 sc-207848
sc-207848A
sc-207848B
sc-207848C
sc-207848D
sc-207848E
1 g
5 g
25 g
100 g
250 g
1 kg
$53.00
$60.00
$200.00
$660.00
$1,140.00
$3,425.00
9
(2)
Spermidine
Spermidine is a NOS1 inhibitor and NMDA and T4 polynucleotide kinase activator
124-20-9 sc-215900
sc-215900A
sc-215900B
1 g
5 g
25 g
$32.00
$109.00
$372.00
0
(2)
Carboxy-PTIO, potassium salt
Carboxy-PTIO, potassium salt is a water soluble and stable nitric oxide radical scavenger which reacts with nitric oxide
148819-94-7 sc-202985
sc-202985A
sc-202985B
10 mg
50 mg
250 mg
$60.00
$185.00
$700.00
10
(1)
1,4-PB-ITU dihydrobromide
1,4-PB-ITU dihydrobromide is a potent inhibitor of NOS
157254-60-9 sc-202003
sc-202003A
10 mg
50 mg
$20.00
$58.00
0
(0)
α-Guanidinoglutaric acid
α-Guanidinoglutaric acid is a linear mixed-type inhibitor of NOS1
73477-53-9 sc-202031
10 mg
$53.00
0
(0)
AMT HYDROCHLORIDE
AMT Hydrochloride is a potent and selective NOS2 inhibitor
21463-31-0 sc-202052
sc-202052A
10 mg
50 mg
$109.00
$419.00
0
(1)
Bakuchiol
Bakuchiol is a PTP1B and DNA polymerase inhibitor
10309-37-2 sc-202075
1 mg
$45.00
1
(1)
Calmidazolium chloride
Calmidazolium chloride is a CaM and calcium channel protein inhbitor
57265-65-3 sc-201494
sc-201494A
10 mg
50 mg
$135.00
$550.00
24
(1)
2-Imino-4-methylpiperidine acetate
2-Imino-4-methylpiperidine acetate is a specific inhibitor of inducible nitric oxide synthase
165383-72-2 sc-202402
sc-202402A
5 mg
25 mg
$30.00
$90.00
0
(0)
2,4-Diamino-6-hydroxypyrimidine
2,4-Diamino-6-hydroxypyrimidine is a selective GTP cyclohydrolase I inhibitor
56-06-4 sc-202404
sc-202404A
250 mg
1 g
$21.00
$40.00
0
(0)
S-(2-Aminoethyl)-ITU dihydrobromide
S-(2-Aminoethyl)-ITU dihydrobromide is a selective inhibitor of NOS2 (iNOS)
56-10-0 sc-202798
sc-202798A
sc-202798B
10 mg
100 mg
1 g
$20.00
$25.00
$30.00
0
(0)
2-Amino-4-methylpyridine
2-Amino-4-methylpyridine is a potent inhibitor of NOS2 (iNOS)
695-34-1 sc-202879
1 g
$31.00
0
(0)
Aminoguanidine hemisulfate
Aminoguanidine hemisulfate is a NOS (nitric oxide synthase) inhibitor
996-19-0 sc-202930
sc-202930A
100 mg
500 mg
$20.00
$30.00
0
(0)
Aminoguanidine hydrochloride
Aminoguanidine hydrochloride is an irreversible and selective inhibitor of NOS2
1937-19-5 sc-202931
sc-202931A
sc-202931B
10 g
25 g
50 g
$30.00
$41.00
$90.00
2
(0)
Artemisinin
Artemisinin is an antimalarial agent that inhibits VEGF expression and NOS2
63968-64-9 sc-202960
sc-202960A
100 mg
1 g
$43.00
$242.00
1
(1)
Canavanine sulfate
Canavanine sulfate is an inhibitor of NOS2
2219-31-0 sc-202983
sc-202983A
sc-202983B
sc-202983C
100 mg
500 mg
1 g
5 g
$50.00
$175.00
$210.00
$750.00
0
(1)
2-Iminopiperidine hydrochloride
2-Iminopiperidine hydrochloride is a selective inhibitor of NOS2
16011-96-4 sc-203462
10 mg
$109.00
1
(0)
Pentamidine isethionate
Pentamidine isethionate is an NMDA Glu antagonist and NOS1 inhibitor
140-64-7 sc-204176
50 mg
$72.00
1
(1)
S-Isopropylisothiourea hydrobromide
S-Isopropylisothiourea hydrobromide is a selective NOS2 inhibitor
57200-31-4 sc-204252
sc-204252A
10 mg
50 mg
$85.00
$359.00
0
(0)
MEG (sulfate)
MEG (sulfate) is a selective NOS2 inhibitor
3979-00-8 sc-205381
sc-205381A
5 mg
10 mg
$110.00
$158.00
0
(0)
Methyl-L-NIO Hydrochloride
A competitive NOS inhibitor
150403-96-6 sc-205389
sc-205389A
5 mg
10 mg
$66.00
$126.00
0
(0)
S-(3-Aminopropyl)-ITU dihydrobromide
S-(3-Aminopropyl)-ITU dihydrobromide is a selective NOS2 inhibitor
7072-40-4 sc-205971
sc-205971A
10 mg
50 mg
$30.00
$62.00
0
(0)
Gabexate mesylate
Gabexate mesylate is an inhibitor of Factor X
56974-61-9 sc-215066
5 mg
$100.00
0
(0)
Allicin
Allicin is a compound that exhibits anticancer, antioxidative, cardioprotective, antihypertensive, anti-arrhythmic, anti-parasitic, and anti-diabetic activities activity.
539-86-6 sc-202449
sc-202449A
1 mg
5 mg
$450.00
$1,400.00
4
(1)
S-Ethyl N-[4-Triflurormethyl)phenyl]isothiourea, Hydrochloride
163490-78-6 sc-208325
10 mg
$260.00
0
(0)
S-Methyl-L-thiocitrulline acetate salt
S-Methyl-L-thiocitrulline acetate salt is a NOS2, NOS1, and NOS3 inhibitor
174063-92-4 sc-215830
sc-215830A
10 mg
50 mg
$85.00
$275.00
1
(0)
1,3-PB-ITU dihydrobromide
1,3-PB-ITU dihydrobromide is a selective inhibitor for NOS2
sc-220549
10 mg
$20.00
0
(0)
3-Bromo-7-nitroindazole sodium salt
3-Bromo-7-nitroindazole sodium salt is a potent NOS1 inhibitor
74209-34-0 free base sc-220856
sc-220856A
sc-220856B
25 mg
100 mg
500 mg
$200.00
$100.00
$400.00
0
(0)
7-Nitroindazole sodium salt
7-Nitroindazole sodium salt is an inhibitor of NOS1 (nNOS)
2942-42-9 (non-salt) sc-221114
sc-221114A
5 mg
25 mg
$23.00
$47.00
1
(0)
Iromycin A
Iromycin A is an inhibitor of NOS showing selectivity for NOS3 (eNOS) versus NOS1 (nNOS)
213137-53-2 sc-221763
sc-221763A
500 µg
1 mg
$444.00
$638.00
0
(0)
MEG sodium succinate
MEG sodium succinate is an NOS2 (iNOS) inhibitor and a peroxynitrite scavenger
1190-74-5 (non-salt) sc-221879
10 mg
$200.00
0
(0)
NG-Monomethyl-L-homoarginine monoacetate
NG-Monomethyl-L-homoarginine monoacetate is NG-Monomethyl-L-homoarginine monoacetate is an inhibitor of NOS.
sc-222069
5 mg
$50.00
0
(0)
NG-Amino-L-arginine hydrochloride
NG-Amino-L-arginine hydrochloride is a potent inhibitor of NOS1, NOS2, and NOS3
1031799-40-2 sc-222066
5 mg
$50.00
0
(0)
NG, N′G-Dimethyl-L-arginine dihydrochloride
NG, N′G-Dimethyl-L-arginine dihydrochloride is a compound not found to inhibit NOS
sc-222070
sc-222070A
5 mg
25 mg
$50.00
$100.00
1
(0)
Propenyl-L-NIO (hydrochloride)
Propenyl-L-NIO (hydrochloride) is a selective inhibitor of NOS2 (iNOS)
sc-222191
sc-222191A
5 mg
10 mg
$67.00
$127.00
0
(0)
S-Ethyl-N-[4-(trifluoromethyl)phenyl]isothiourea hydrochloride
S-Ethyl-N-[4-(trifluoromethyl)phenyl]isothiourea hydrochloride is a NOS inhibitor
163490-78-6 sc-222274
sc-222274A
5 mg
25 mg
$23.00
$82.00
0
(0)
Ethyl-L-NIO, hydrochloride
Ethyl-L-NIO, hydrochloride is a selective NOS1 inhibitor
150403-97-7 sc-223979
sc-223979A
5 mg
10 mg
$56.00
$107.00
0
(0)
N-omega-Propyl-L-Arginine
N-ω-Propyl-L-Arginine is a selective inhibitor of NOS1
137361-05-8 sc-224171
sc-224171A
5 mg
10 mg
$65.00
$180.00
0
(0)
N-(5-Amino-5-carboxypentyl)acetamidine
53774-63-3 sc-295591
sc-295591A
1 g
5 g
$280.00
$1,130.00
0
(0)
N-Benzylacetamidine Hydrobromide
N-Benzylacetamidine Hydrobromide is a NOS2 inhibitor
186545-76-6 sc-295668
sc-295668A
5 mg
10 mg
$104.00
$149.00
0
(0)
1-Amino-2-hydroxyguanidine, p-Toluenesulfonate
1-Amino-2-hydroxyguanidine, p-Toluenesulfonate is a potent inhibitor of NOS2 (iNOS)
sc-3565
10 mg
$200.00
1
(0)
S-Methylisothiourea sulfate
S-Methylisothiourea sulfate is a potent and selective iNOS and NOS2 inhibitor
867-44-7 sc-3566
sc-3566A
1 g
100 g
$20.00
$23.00
8
(2)
1,3-PBITU, Dihydrobromide
1,3-PBITU, Dihydrobromide is a potent competitive inhibitor of NOS with NOS2 selectivity
sc-3568
10 mg
$20.00
1
(1)
7-Nitroindazole
7-Nitroindazole is a specific inhibitor of neural nitric oxide synthase (nNOS)
2942-42-9 sc-3569
100 mg
$70.00
4
(2)
N G-Nitro-L-arginine
N G-Nitro-L-arginine is an inhibitor of NOS with selectivity for NOS1 and NOS3
2149-70-4 sc-3570
1 g
$19.00
4
(1)
S-Methyl-L thiocitrulline, Dihydrochloride
S-Methyl-L thiocitrulline, Dihydrochloride is a potent inhibitor of NOS1 and NOS3
209589-59-3 sc-3571
10 mg
$56.00
1
(1)
L-thiocitrulline, Dihydrochloride
L-thiocitrulline, Dihydrochloride is an inhibitor of NOS1, NOS2, and NOS3
212051-53-1 sc-3572
sc-3572A
10 mg
50 mg
$62.00
$245.00
0
(0)
Spermidine trihydrochloride
Spermidine trihydrochloride is a NOS1 inhibitor and NMDA and T4 activator
334-50-9 sc-360822
sc-360822A
1 g
5 g
$40.00
$110.00
0
(0)
ARL 17477 dihydrochloride
ARL 17477 dihydrochloride is a selective NOS1 inhibitor
866914-87-6 sc-361108
sc-361108A
10 mg
50 mg
$129.00
$548.00
0
(0)
BYK 191023 dihydrochloride
BYK 191023 dihydrochloride is a selective inhibitor of NOS2
608880-48-4 sc-361131
sc-361131A
10 mg
50 mg
$155.00
$660.00
3
(1)
L-NIO dihydrochloride
L-NIO dihydrochloride is a potent inhibitor of NOS1, NOS2, and NOS3
36889-13-1 sc-361229
sc-361229A
10 mg
50 mg
$59.00
$205.00
5
(0)
L-NMMA (citrate)
L-NMMA (citrate) is a non-selective inhibitor of NOS
sc-364686
sc-364686A
sc-364686B
10 mg
50 mg
100 mg
$56.00
$252.00
$450.00
1
(0)
L-Canavanine
L-Canavanine is a selective inhibitor of NOS2
543-38-4 sc-364687
sc-364687A
250 mg
1 g
$179.00
$544.00
0
(1)
ARL-17477 dihydrochloride
ARL-17477 dihydrochloride is A NOS1 (nNOS) inhibitor
866914-87-6 sc-391011
sc-391011A
5 mg
25 mg
$122.00
$500.00
0
(0)
NG-Monoethyl-L-arginine TFA
MF: C8H18N4O2•C2HF3O2, MW: 316.28
sc-391814
sc-391814A
10 mg
100 mg
$120.00
$200.00
0
(0)