9230105E10Rik Inhibitors
Chemical inhibitors of 9230105E10Rik can effectively modulate the function of this protein through various biochemical pathways by directly blocking the activity of kinases and other enzymes that are crucial for its regulation and stability. Staurosporine, a broad-spectrum protein kinase inhibitor, can inhibit the phosphorylation of 9230105E10Rik, thereby preventing its activation. Similarly, Bisindolylmaleimide I targets Protein Kinase C isoforms, which, if involved in the activation or stability of 9230105E10Rik, would result in its downregulation upon inhibition. LY294002 and Wortmannin both inhibit PI3K, a kinase that can activate several downstream targets, potentially including those that regulate 9230105E10Rik. By preventing PI3K activity, these inhibitors can disrupt the signaling cascade necessary for the proper functioning of 9230105E10Rik.
Further down the signaling pathways, PD98059 and U0126, both MEK1/2 inhibitors, can obstruct the MAPK/ERK pathway, which may be integral to the regulation of 9230105E10Rik. The p38 MAP kinase, targeted by SB203580, plays a vital role in inflammatory responses and its inhibition can affect 9230105E10Rik if its activity is linked to this signaling route. SP600125, which inhibits JNK, can also prevent signaling events crucial for the function of 9230105E10Rik. Additionally, Rapamycin's inhibition of mTOR, a central regulator of cell growth, can suppress the activity of 9230105E10Rik if mTOR signaling is part of its regulatory mechanism. Lastly, PP2, Dasatinib, and Imatinib, which inhibit Src family kinases, Bcr-Abl, and PDGF receptor respectively, can obstruct the phosphorylation and activation of 9230105E10Rik by targeting these specific kinases that may be involved in its activation or stability. By employing these inhibitors, the activity of 9230105E10Rik can be modulated based on its dependence on these various signaling molecules and pathways.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine is a potent inhibitor of a wide range of protein kinases, which could include those that phosphorylate 9230105E10Rik, altering its activity state and thus functionally inhibiting it by preventing its proper phosphorylation. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
Bisindolylmaleimide I selectively inhibits Protein Kinase C (PKC) isoforms. If PKC is required for the activation or stability of 9230105E10Rik, its inhibition would result in the functional inhibition of 9230105E10Rik. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is an inhibitor of PI3K. By inhibiting PI3K, LY294002 can prevent the activation of downstream targets that may be necessary for the functional activity of 9230105E10Rik, thereby inhibiting its function. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is another PI3K inhibitor that can prevent the phosphorylation and activation of downstream proteins that would otherwise contribute to the functional activity of 9230105E10Rik, leading to its inhibition. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 selectively inhibits MEK1/2, which are upstream of ERK in the MAPK pathway. The inhibition of this pathway can reduce the functional activity of 9230105E10Rik if the MAPK pathway is involved in its regulation. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a specific inhibitor of p38 MAP kinase. Inhibition of p38 MAP kinase can decrease the functional activity of 9230105E10Rik if p38 MAP kinase signaling is required for the full activity of this protein. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 inhibits JNK, and by doing so, it can block signaling events that are crucial for the functional activity of 9230105E10Rik, if JNK signaling is implicated in its regulation. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, which is a central regulator of cell growth and proliferation. The inhibition of mTOR can result in the functional inhibition of 9230105E10Rik if mTOR signaling is involved in the regulation or stability of this protein. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $92.00 $223.00 | 30 | |
PP2 is a Src family kinase inhibitor. If Src kinases phosphorylate, regulate, or otherwise influence the functional activity of 9230105E10Rik, then PP2 can functionally inhibit 9230105E10Rik by inhibiting Src family kinases. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Dasatinib is a Bcr-Abl and Src family kinase inhibitor that can functionally inhibit 9230105E10Rik by blocking the kinase activity necessary for its activation or stability, if Bcr-Abl or Src kinases are involved in the regulation of the protein. | ||||||