Date published: 2026-5-13

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52 kDa Ro/SSA Inhibitors

52 kDa Ro/SSA inhibitors belong to a specific chemical class of compounds meticulously designed to modulate the activity of the 52 kDa Ro/SSA protein, also known as Sjögren syndrome antigen A1 (SSA1). The 52 kDa Ro/SSA protein is an autoantigen that is associated with autoimmune diseases such as Sjögren's syndrome and systemic lupus erythematosus. These inhibitors are thoughtfully crafted molecules engineered to interact with the 52 kDa Ro/SSA protein, influencing its normal function. Through these interactions, they might impact various cellular processes associated with autoimmunity, immune responses, and cellular reactions, without directly altering its epitopes or its involvement in autoimmune mechanisms. The design of 52 kDa Ro/SSA inhibitors is grounded in a comprehensive understanding of the structural and functional attributes of the 52 kDa Ro/SSA protein. Typically developed using advanced chemical synthesis methods and informed by insights from immunology and autoimmune diseases, these inhibitors are characterized by their ability to selectively bind to the 52 kDa Ro/SSA protein. This selectivity enables focused modulation of cellular pathways that rely on the activity of this specific autoantigen. Unraveling the intricacies of autoimmunity, immune regulation, and cellular interactions often employ 52 kDa Ro/SSA inhibitors as valuable tools. The development and utilization of 52 kDa Ro/SSA inhibitors contribute to advancing our knowledge of the complex interplay between immune components and autoimmune dynamics, offering insights into the fundamental molecular mechanisms that govern autoimmune responses and contribute to cellular behavior in the context of autoimmune diseases.
Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Ginkgolic acid C15:1

22910-60-7sc-235249
5 mg
$312.00
2
(1)

Inhibits 52 kDa Ro/SSA-mediated ubiquitination and degradation of target proteins.

Lovastatin

75330-75-5sc-200850
sc-200850A
sc-200850B
5 mg
25 mg
100 mg
$29.00
$90.00
$339.00
12
(1)

Modulat 52 kDa Ro/SSA activity through their effects on intracellular pathways.

Niclosamide

50-65-7sc-250564
sc-250564A
sc-250564B
sc-250564C
sc-250564D
sc-250564E
100 mg
1 g
10 g
100 g
1 kg
5 kg
$38.00
$79.00
$188.00
$520.00
$1248.00
$5930.00
8
(1)

Exhibits effects on 52 kDa Ro/SSA-related processes through its mode of action.

Oltipraz

64224-21-1sc-205777
sc-205777A
500 mg
1 g
$286.00
$622.00
(1)

May interfere with 52 kDa Ro/SSA-associated cellular processes.

Curcumin

458-37-7sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$37.00
$69.00
$109.00
$218.00
$239.00
$879.00
$1968.00
47
(1)

Exhibits potential interactions with 52 kDa Ro/SSA-related pathways.

Metronidazole

443-48-1sc-204805
sc-204805A
5 g
25 g
$84.00
$205.00
11
(2)

May modulate 52 kDa Ro/SSA-associated processes through indirect effects.

Thalidomide

50-35-1sc-201445
sc-201445A
100 mg
500 mg
$111.00
$357.00
8
(0)

Demonstrates effects on 52 kDa Ro/SSA-mediated processes in certain contexts.