5 α-Reductase Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Finasteride 2-(2-Methylpropanol)amide | 116285-36-0 | sc-207685 | 5 mg | $380.00 | ||
Finasteride 2-(2-Methylpropanol)amide exhibits intriguing characteristics as a 5 alpha-reductase inhibitor, primarily through its ability to form hydrogen bonds with key amino acid residues in the enzyme's active site. This interaction stabilizes the enzyme-substrate complex, effectively modulating enzymatic activity. Additionally, its steric configuration allows for selective binding, influencing the reaction kinetics and enhancing its specificity in biochemical pathways. The compound's lipophilic nature further affects its solubility and distribution in biological systems. | ||||||
Elaiophylin | 37318-06-2 | sc-202147 sc-202147A sc-202147B sc-202147C sc-202147D sc-202147E | 1 mg 5 mg 10 mg 25 mg 50 mg 100 mg | $192.00 $440.00 $544.00 $1067.00 $1944.00 $3420.00 | 1 | |
Elaiophylin functions as a 5 alpha-reductase inhibitor by engaging in unique hydrophobic interactions with the enzyme's active site, which alters the conformational dynamics of the protein. Its distinct molecular structure facilitates competitive inhibition, impacting the enzyme's catalytic efficiency. The compound's ability to form transient complexes with the enzyme enhances its selectivity, while its unique electronic properties influence the overall reaction mechanism, contributing to its efficacy in biochemical processes. | ||||||
Ethyl 4-Bromomethylcinnamate | 60682-98-6 | sc-394089 | 2.5 mg | $330.00 | ||
Ethyl 4-Bromomethylcinnamate exhibits its role as a 5 alpha-reductase inhibitor through specific steric hindrance and electronic modulation of the enzyme's active site. The presence of the bromomethyl group introduces unique steric effects that disrupt substrate binding, while the ethyl ester enhances lipophilicity, promoting membrane permeability. This compound's reactivity profile allows for selective interactions, influencing the enzyme's kinetic parameters and altering metabolic pathways effectively. | ||||||
Finasteride Carboxylic Acid | 116285-37-1 | sc-207686 | 2.5 mg | $470.00 | ||
Finasteride Carboxylic Acid functions as a 5 alpha-reductase inhibitor by engaging in unique hydrogen bonding interactions with the enzyme's active site, stabilizing the transition state and reducing enzymatic activity. Its carboxylic acid moiety enhances solubility in aqueous environments, facilitating interactions with polar residues. The compound's distinct steric configuration influences binding affinity, leading to altered reaction kinetics and modulation of androgen metabolism pathways. | ||||||
3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid | 104239-97-6 | sc-206676 | 1 g | $260.00 | ||
3-Oxo-4-aza-5α-androst-1-ene-17β-carboxylic Acid acts as a 5 alpha-reductase inhibitor through specific electrostatic interactions with the enzyme's active site, which disrupts substrate binding. The presence of the aza group introduces unique steric hindrance, affecting the enzyme's conformation and catalytic efficiency. Additionally, the compound's carboxylic acid functionality promotes ionic interactions, enhancing its affinity for the enzyme and influencing metabolic pathways related to androgen synthesis. | ||||||
Finasteride-d9 | 98319-26-7 (unlabeled) | sc-218478 | 1 mg | $330.00 | 1 | |
Finasteride-d9 functions as a 5 alpha-reductase inhibitor by engaging in selective hydrogen bonding with key amino acid residues in the enzyme's active site. Its deuterated structure alters the kinetic isotope effect, potentially enhancing the stability of enzyme-inhibitor complexes. The compound's unique hydrophobic regions facilitate van der Waals interactions, modulating enzyme dynamics and influencing the overall catalytic mechanism, thereby impacting androgen metabolism. | ||||||