Molecular structure of 3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid, CAS Number: 104239-97-6
3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid (CAS 104239-97-6)
Alternate Names:
(4aR,4bS,6aS,7S,9aS,9bS,11aR)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxylic Acid
Application:
3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid is A novel intermediate in the synthesis of FInasteride
CAS Number:
104239-97-6
Molecular Weight:
317.42
Molecular Formula:
C19H27NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A novel intermediate in the synthesis of Finasteride, a 5α-reductase inhibitor used for treatment of benign prostatic hyperplasia acne, seborrhea, female hirsutism, prostatitis, and prostatic carcinoma and other hyperandrogenetic related disorders.
3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid (CAS 104239-97-6) References
- Synthesis and bioactivity of new Finasteride conjugate. | Shuang, Z., et al. 2011. Bioorg Med Chem Lett. 21: 3439-42. PMID: 21515045
- Azasteroids: structure-activity relationships for inhibition of 5 alpha-reductase and of androgen receptor binding. | Rasmusson, GH., et al. 1986. J Med Chem. 29: 2298-315. PMID: 3783591
- 4-Aza-3-oxo-5 alpha-androst-1-ene-17 beta-N-aryl-carboxamides as dual inhibitors of human type 1 and type 2 steroid 5 alpha-reductases. Dramatic effect of N-aryl substituents on type 1 and type 2 5 alpha-reductase inhibitory potency. | Bakshi, RK., et al. 1995. J Med Chem. 38: 3189-92. PMID: 7650670
Inhibitor of:
5 α-Reductase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-Oxo-4-aza-5α-αndrost-1-ene-17β-carboxylic Acid, 1 g | sc-206676 | 1 g | $260.00 |