Molecular structure of Finasteride Carboxylic Acid, CAS Number: 116285-37-1
Finasteride Carboxylic Acid (CAS 116285-37-1)
Alternate Names:
2-Methyl-N-[[(5a,17b)-3-oxo-4-azaandrost-1-en-17-yl]carbonyl]alanine
Application:
Finasteride Carboxylic Acid is A metabolite of Finasteride and an inhibitor of 5α-reductase.
CAS Number:
116285-37-1
Molecular Weight:
402.53
Molecular Formula:
C23H34N2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Finasteride Carboxylic Acid functions as a potent inhibitor of the enzyme 5-alpha reductase. This enzyme is responsible for the conversion of testosterone to dihydrotestosterone (DHT). By inhibiting this enzyme, Finasteride Carboxylic Acid effectively reduces the levels of DHT, which is known to contribute to the development of benign prostatic hyperplasia (BPH) and androgenic alopecia. At the molecular level, Finasteride Carboxylic Acid binds to the active site of 5-alpha reductase, preventing the conversion of testosterone to DHT. Finasteride Carboxylic Acid′s mechanism of action can be studied to gain insights into the biochemical pathways involved in the regulation of androgen hormones.
Finasteride Carboxylic Acid (CAS 116285-37-1) References
- Disposition and pharmacokinetics of [14C]finasteride after oral administration in humans. | Carlin, JR., et al. 1992. Drug Metab Dispos. 20: 148-55. PMID: 1352203
- Doping-control analysis of the 5alpha-reductase inhibitor finasteride: determination of its influence on urinary steroid profiles and detection of its major urinary metabolite. | Thevis, M., et al. 2007. Ther Drug Monit. 29: 236-47. PMID: 17417080
- Identification of finasteride metabolites in human bile and urine by high-performance liquid chromatography/tandem mass spectrometry. | Lundahl, A., et al. 2009. Drug Metab Dispos. 37: 2008-17. PMID: 19635781
- A simple and rapid ESI-LC-MS/MS method for simultaneous screening of doping agents in urine samples. | Reddy, IM., et al. 2009. Indian J Pharmacol. 41: 80-6. PMID: 20336223
- A rapid screening LC-MS/MS method based on conventional HPLC pumps for the analysis of low molecular weight xenobiotics: application to doping control analysis. | Mazzarino, M., et al. 2010. Drug Test Anal. 2: 311-22. PMID: 20818799
- Current treatment of BPH. | Roylance, P., et al. 1995. Biomed Pharmacother. 49: 332-8. PMID: 8562858
Inhibitor of:
5 α-Reductase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Finasteride Carboxylic Acid, 2.5 mg | sc-207686 | 2.5 mg | $470.00 |