Molecular structure of Finasteride 2-(2-Methylpropanol)amide, CAS Number: 116285-36-0
Finasteride 2-(2-Methylpropanol)amide (CAS 116285-36-0)
Application:
Finasteride 2-(2-Methylpropanol)amide is a metabolite of Finasteride and an inhibitor of 5α-reductase
CAS Number:
116285-36-0
Molecular Weight:
388.54
Molecular Formula:
C23H36N2O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
A metabolite of Finasteride (M-1 metabolite). Acts as an inhibitor of 5α-reductase, the enzyme which converts testosterone to the more potent androgen, 5α-dihydrotestosterone.
Finasteride 2-(2-Methylpropanol)amide (CAS 116285-36-0) References
- Disposition and pharmacokinetics of [14C]finasteride after oral administration in humans. | Carlin, JR., et al. 1992. Drug Metab Dispos. 20: 148-55. PMID: 1352203
- Identification of finasteride metabolites in human bile and urine by high-performance liquid chromatography/tandem mass spectrometry. | Lundahl, A., et al. 2009. Drug Metab Dispos. 37: 2008-17. PMID: 19635781
- Determination of finasteride and its metabolite in urine by dispersive liquid-liquid microextraction combined with field-enhanced sample stacking and sweeping. | Chen, CH., et al. 2018. J Chromatogr A. 1547: 14-20. PMID: 29534820
- Current treatment of BPH. | Roylance, P., et al. 1995. Biomed Pharmacother. 49: 332-8. PMID: 8562858
- Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride. | Huskey, SW., et al. 1995. Drug Metab Dispos. 23: 1126-35. PMID: 8654202
- Effects of the anti-androgen finasteride on 5alpha-reductase activity in human gingival fibroblasts in response to minocycline. | Soory, M. and Virdi, H. 1998. J Clin Periodontol. 25: 67-73. PMID: 9477022
Inhibitor of:
5 α-Reductase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Finasteride 2-(2-Methylpropanol)amide, 5 mg | sc-207685 | 5 mg | $380.00 |