1700011A15Rik Inhibitors
Chemical inhibitors of 1700011A15Rik function through various mechanisms to inhibit the protein's activity by targeting different signaling pathways within cells. Wortmannin and LY294002 are two such inhibitors that act on the PI3K/Akt pathway, which is vital for numerous cellular functions. By obstructing this pathway, these inhibitors lead to a reduction in Akt phosphorylation. This in turn can inhibit the downstream signaling that may be essential for the functionality of 1700011A15Rik. Similarly, Rapamycin disrupts the mTOR signaling pathway, which is another crucial pathway for cellular growth and protein synthesis. By inhibiting mTOR, Rapamycin can affect the cellular processes that are dependent on this pathway, where 1700011A15Rik is involved, leading to an inhibition of its function.
On another front, Dasatinib and PP2 target the Src family kinases. These kinases are part of a larger group of tyrosine kinases that play significant roles in signal transduction. The inhibition of these kinases can disrupt the downstream signaling pathways that involve 1700011A15Rik, thereby inhibiting the protein's function. Moreover, U0126, PD98059, and SL327 are MEK inhibitors that function by blocking the MAPK/ERK pathway. The MAPK/ERK pathway is integral for cell proliferation and differentiation, and its inhibition can affect the functional activity of 1700011A15Rik. Further, SB203580 and SP600125 inhibit the p38 MAPK and JNK signaling pathways, respectively, which are implicated in stress responses, cytokine production, inflammation, and apoptosis. The inhibition of these pathways can disrupt the processes where 1700011A15Rik is functionally involved. Lastly, Y-27632 and PD173074 target the Rho/ROCK pathway and the FGFR signaling pathways, respectively. The Rho/ROCK pathway is known for its role in cytoskeletal organization, and FGFR signaling is important for processes such as cell growth and differentiation. Inhibiting these pathways can lead to functional inhibition of 1700011A15Rik, which may be involved in these cellular functions.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin, a PI3K inhibitor, can functionally inhibit 1700011A15Rik by obstructing the PI3K/Akt pathway, which is crucial for several cellular processes including those involving 1700011A15Rik. Inhibition of PI3K leads to a decrease in Akt phosphorylation and subsequent downstream signaling that may be vital for 1700011A15Rik's activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is an mTOR inhibitor that can functionally inhibit 1700011A15Rik by disrupting the mTOR signaling pathway. Since mTOR is involved in protein synthesis and cell growth, its inhibition can affect the cellular processes where 1700011A15Rik is involved, leading to a reduction in its functional activity. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $70.00 $145.00 | 51 | |
Dasatinib, a tyrosine kinase inhibitor, functionally inhibits 1700011A15Rik by targeting Src family kinases. By inhibiting these kinases, Dasatinib can disrupt downstream signaling pathways where 1700011A15Rik may play a role, thereby inhibiting the protein's function. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126, a MEK inhibitor, can functionally inhibit 1700011A15Rik by blocking the MAPK/ERK pathway. This inhibition can affect cellular functions such as proliferation and differentiation where 1700011A15Rik is involved, leading to a functional inhibition of the protein. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002, another PI3K inhibitor, can functionally inhibit 1700011A15Rik by impeding the PI3K/Akt signaling pathway. The disruption of this pathway can lead to an inhibition of the functions where 1700011A15Rik is involved, particularly if PI3K/Akt signaling is essential for its activity. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580, a p38 MAP kinase inhibitor, can functionally inhibit 1700011A15Rik by blocking p38 MAPK signaling. As p38 MAPK is involved in stress responses and cytokine production, its inhibition can disrupt processes where 1700011A15Rik is functionally involved. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125, a JNK inhibitor, can functionally inhibit 1700011A15Rik by impeding the JNK signaling pathway. JNK pathway is implicated in various cellular processes including inflammation and apoptosis where 1700011A15Rik could be functionally involved. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059, a MEK inhibitor like U0126, can functionally inhibit 1700011A15Rik by blocking the MAPK/ERK pathway. This inhibition can lead to the functional downregulation of cellular activities where 1700011A15Rik is involved. | ||||||
PP 2 | 172889-27-9 | sc-202769 sc-202769A | 1 mg 5 mg | $94.00 $227.00 | 30 | |
PP2, a Src family tyrosine kinase inhibitor, can functionally inhibit 1700011A15Rik by disrupting the signaling pathways that depend on the kinase activity of Src family members, potentially inhibiting the functional aspects of 1700011A15Rik involved in these pathways. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
Y-27632, a ROCK inhibitor, can functionally inhibit 1700011A15Rik by blocking the Rho/ROCK pathway. The Rho/ROCK pathway plays a significant role in cytoskeletal organization, and its inhibition could affect the cellular processes where 1700011A15Rik is active. | ||||||