Date published: 2025-11-1

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1300002K09Rik Inhibitors

STRA6, short for Stimulated by Retinoic Acid 6, is a protein that plays a pivotal role in the cellular uptake of vitamin A from the bloodstream. Vitamin A, also known as retinol, is essential for various physiological processes, including vision, reproduction, cellular differentiation, and immune system function. STRA6 functions as a high-affinity receptor for the retinol-binding protein (RBP), facilitating the transfer of retinol from RBP to cells, a process crucial for maintaining vitamin A homeostasis in the body. The STRA6-like category refers to proteins or receptors that share structural or functional similarities with STRA6, suggesting they might play a role in similar pathways or have overlapping functions.

STRA6-like inhibitors are compounds designed to target and modulate the activity of STRA6-like proteins. By interacting with these proteins, these inhibitors influence the cellular uptake and processing of vitamin A, thereby affecting the pathways and processes dependent on this vitamin. The chemical properties and structures of these inhibitors may vary, but they all aim to alter the normal function of STRA6-like proteins. Studying such inhibitors provides an avenue to understand the precise roles of STRA6-like proteins in cellular physiology. Moreover, these inhibitors can serve as invaluable tools for researchers, helping to dissect and elucidate the molecular intricacies of vitamin A metabolism and the broader implications of STRA6-like proteins in cellular function. The development and characterization of STRA6-like inhibitors will undoubtedly contribute to the broader understanding of vitamin A homeostasis and its intricate regulatory mechanisms.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Citral

5392-40-5sc-252620
1 kg
$212.00
(1)

Citral is known to inhibit retinoic acid synthesis, potentially affecting STRA6L expression.

Disulfiram

97-77-8sc-205654
sc-205654A
50 g
100 g
$52.00
$87.00
7
(1)

Known to inhibit retinal dehydrogenase and may thus alter STRA6L expression.

Bexarotene

153559-49-0sc-217753
sc-217753A
10 mg
100 mg
$54.00
$245.00
6
(1)

An RXR selective retinoid that may influence STRA6L expression through retinoid signaling.

LE 135

155877-83-1sc-204053
sc-204053A
10 mg
50 mg
$168.00
$707.00
5
(1)

An antagonist of RARβ, it might modulate STRA6L expression indirectly.

4-Hydroxyphenylretinamide

65646-68-6sc-200900
sc-200900A
5 mg
25 mg
$104.00
$315.00
(0)

A synthetic retinoid derivative; its modulation of the retinoid pathway might affect STRA6L.

Diethyl(3-pyridyl)borane

89878-14-8sc-234676
10 g
$168.00
(0)

Inhibits retinoic acid metabolism, potentially affecting STRA6L.

MM 11253

345952-44-5sc-361255
sc-361255A
10 mg
50 mg
$468.00
$2000.00
2
(1)

A synthetic retinoid which might modulate the expression of STRA6L through the retinoid pathway.