Date published: 2025-10-10

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ANKRD18A Inibidores

ANKRD18A inhibitors represent a specialized class of chemical compounds designed to modulate the activity of the ANKRD18A protein, which is involved in various cellular processes. This protein, characterized by the presence of ankyrin repeat domains, plays a crucial role in protein-protein interactions and the regulation of cellular signaling pathways. ANKRD18A inhibitors typically feature a diverse range of chemical structures, often comprising heterocyclic rings, aromatic systems, and specific functional groups that enhance binding affinity and selectivity for the target protein. The design of these inhibitors focuses on optimizing their interaction with the ANKRD18A protein, often employing techniques such as molecular docking and structure-activity relationship studies to identify optimal chemical scaffolds.

The approaches to creating ANKRD18A inhibitors often involve advanced chemistry methods, including multi-step synthesis and combinatorial chemistry. These inhibitors may exhibit varying degrees of potency and specificity, which are essential for understanding the biological roles of ANKRD18A in cellular contexts. Furthermore, the study of these compounds contributes to the broader understanding of cellular mechanisms by providing tools to dissect the functions of ANKRD18A. Research into this chemical class also involves examining the physicochemical properties of the compounds, such as solubility, stability, and permeability, to ensure their suitability for experimental applications. As a result, ANKRD18A inhibitors serve as valuable resources for researchers investigating the fundamental biology of the ANKRD18A protein and its involvement in various cellular processes.

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Nome do ProdutoCAS #Numero de CatalogoQuantidadePrecoUso e aplicacaoNOTAS

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$73.00
$238.00
$717.00
$2522.00
$21420.00
53
(3)

Este antibiótico liga-se ao ADN e inibe a ARN polimerase, diminuindo potencialmente a síntese do ARNm do ANKRD18A.

Cycloheximide

66-81-9sc-3508B
sc-3508
sc-3508A
100 mg
1 g
5 g
$40.00
$82.00
$256.00
127
(5)

Este composto inibe a síntese proteica ao bloquear a translocação durante a tradução, reduzindo potencialmente os níveis da proteína ANKRD18A.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

Como inibidor de mTOR, a rapamicina regula negativamente as vias de síntese proteica, o que pode afetar a expressão de ANKRD18A.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

Este análogo da citidina afecta a metilação do ADN, o que pode levar a uma alteração da expressão de genes, incluindo o ANKRD18A.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

Ao inibir as histonas desacetilases, afecta a estrutura da cromatina e a expressão dos genes, tendo um impacto potencial nos níveis de ANKRD18A.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$260.00
$1029.00
26
(2)

Esta toxina inibe a RNA polimerase II, reduzindo potencialmente a transcrição do gene ANKRD18A.

Mycophenolic acid

24280-93-1sc-200110
sc-200110A
100 mg
500 mg
$68.00
$261.00
8
(1)

Inibe a inosina monofosfato desidrogenase, afectando a síntese de nucleótidos e reduzindo potencialmente a síntese de ARN, incluindo a do ANKRD18A.

Anisomycin

22862-76-6sc-3524
sc-3524A
5 mg
50 mg
$97.00
$254.00
36
(2)

Este antibiótico inibe a formação de ligações peptídicas nos ribossomas, o que diminuiria a síntese global de proteínas, incluindo a ANKRD18A.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$57.00
$182.00
$92.00
21
(2)

Inibe a topoisomerase I do ADN, que é necessária para a replicação e transcrição do ADN, afectando potencialmente a expressão de ANKRD18A.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$42.00
$185.00
$310.00
$650.00
6
(1)

Este composto inibe seletivamente a RNA polimerase II, o que pode levar à diminuição da transcrição do gene ANKRD18A.