ZSCAN22 Antibody (D-4): sc-514712
- ZSCAN22 Antibody (D-4) is a mouse monoclonal IgG1 κ ZSCAN22 antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 35-58 near the N-terminus of ZSCAN22 of mouse origin
- ZSCAN22 Antibody (D-4) is recommended for detection of ZSCAN22 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ZSCAN22 Antibody (D-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ZSCAN22 Antibody (D-4) for WB applications. These reagents are now offered in bundles with ZSCAN22 Antibody (D-4) (see ordering information below).
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ZSCAN22 Antibody (D-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects ZSCAN22 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZSCAN22 (D-4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZSCAN22 protein, also known as HKR2 or ZNF50, is a 491 amino acid nuclear protein that plays a crucial role in transcriptional regulation. ZSCAN22 belongs to the Krüppel C2H2-type zinc-finger protein family, characterized by eight C2H2-type zinc fingers and one SCAN box domain, which are essential for DNA-binding capabilities. The presence of these zinc fingers allows ZSCAN22 to interact with specific DNA sequences, thereby influencing gene expression. ZSCAN22 becomes phosphorylated in response to DNA damage, suggesting involvement in cellular stress responses and maintenance of genomic integrity. The gene encoding ZSCAN22 is located on human chromosome 19q13.43, highlighting significance in human genetics and potential implications in various diseases.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZSCAN22 Antibody (D-4) References:
- Clustering of C2-H2 zinc finger motif sequences within telomeric and fragile site regions of human chromosomes. | Lichter, P., et al. 1992. Genomics. 13: 999-1007. PMID: 1505991
- [Effect of yiqijiedu granule on the implanted-tumor protein expression in nasopharyngeal carcinoma]. | Tang, FQ., et al. 2004. Zhong Nan Da Xue Xue Bao Yi Xue Ban. 29: 577-82. PMID: 16137052
- ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. | Matsuoka, S., et al. 2007. Science. 316: 1160-6. PMID: 17525332
- Multiple genes encoding zinc finger domains are expressed in human T cells. | Thiesen, HJ. 1990. New Biol. 2: 363-74. PMID: 2288909
- Zscan10 is dispensable for maintenance of pluripotency in mouse embryonic stem cells. | Yamane, M., et al. 2015. Biochem Biophys Res Commun. 468: 826-31. PMID: 26592664
- [Function and mechanism of zinc finger protein ZNF50 in inhibiting the growth of esophageal squamous cell carcinoma cells]. | Wang, J., et al. 2017. Zhonghua Zhong Liu Za Zhi. 39: 7-12. PMID: 28104026
- The GLI-Kruppel family of human genes. | Ruppert, JM., et al. 1988. Mol Cell Biol. 8: 3104-13. PMID: 2850480
- Finger proteins and DNA-specific recognition: distinct patterns of conserved amino acids suggest different evolutionary modes. | Payre, F. and Vincent, A. 1988. FEBS Lett. 234: 245-50. PMID: 3292287
- Circular RNAs of UDP-Glycosyltransferase (UGT) Genes Expand the Complexity and Diversity of the UGT Transcriptome. | Hu, DG., et al. 2021. Mol Pharmacol. 99: 488-503. PMID: 33824186
- Isolation of cDNA clones for 42 different Krüppel-related zinc finger proteins expressed in the human monoblast cell line U-937. | Abrink, M., et al. 1995. DNA Cell Biol. 14: 125-36. PMID: 7865130
- Zinc fingers: conserved properties that can distinguish between spurious and actual DNA-binding motifs. | Rosenfeld, R. and Margalit, H. 1993. J Biomol Struct Dyn. 11: 557-70. PMID: 8129873
- Assignment of the human GLI2 gene to 2q14 by fluorescence in situ hybridization. | Matsumoto, N., et al. 1996. Genomics. 36: 220-1. PMID: 8812445
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZSCAN22 Antibody (D-4) | sc-514712 | 200 µg/ml | $316.00 | |||
ZSCAN22 Antibody (D-4): m-IgG Fc BP-HRP Bundle | sc-527933 | 200 µg Ab; 10 µg BP | $354.00 | |||
ZSCAN22 Antibody (D-4): m-IgG1 BP-HRP Bundle | sc-533306 | 200 µg Ab; 20 µg BP | $354.00 | |||
ZSCAN22 Antibody (D-4) AC | sc-514712 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ZSCAN22 Antibody (D-4) HRP | sc-514712 HRP | 200 µg/ml | $316.00 | |||
ZSCAN22 Antibody (D-4) FITC | sc-514712 FITC | 200 µg/ml | $330.00 | |||
ZSCAN22 Antibody (D-4) PE | sc-514712 PE | 200 µg/ml | $343.00 | |||
ZSCAN22 Antibody (D-4) Alexa Fluor® 488 | sc-514712 AF488 | 200 µg/ml | $357.00 | |||
ZSCAN22 Antibody (D-4) Alexa Fluor® 546 | sc-514712 AF546 | 200 µg/ml | $357.00 | |||
ZSCAN22 Antibody (D-4) Alexa Fluor® 594 | sc-514712 AF594 | 200 µg/ml | $357.00 | |||
ZSCAN22 Antibody (D-4) Alexa Fluor® 647 | sc-514712 AF647 | 200 µg/ml | $357.00 | |||
ZSCAN22 Antibody (D-4) Alexa Fluor® 680 | sc-514712 AF680 | 200 µg/ml | $357.00 | |||
ZSCAN22 Antibody (D-4) Alexa Fluor® 790 | sc-514712 AF790 | 200 µg/ml | $357.00 | |||
ZSCAN22 (D-4) Neutralizing Peptide | sc-514712 P | 100 µg/0.5 ml | $68.00 |