ZNF474 Antibody (C-8): sc-514917
- ZNF474 Antibody (C-8) is a mouse monoclonal IgG2a κ ZNF474 antibody provided at 200 µg/ml
- raised against amino acids 191-364 mapping at the C-terminus of ZNF474 of human origin
- ZNF474 Antibody (C-8) is recommended for detection of ZNF474 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-ZNF474 Antibody (C-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ZNF474 Antibody (C-8) for WB and IHC(P) applications. These reagents are now offered in bundles with ZNF474 Antibody (C-8) (see ordering information below).
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SEE ALSO...
ZNF474 Antibody (C-8) is a mouse monoclonal IgG2a kappa light chain antibody that detects ZNF474 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZNF474 (C-8) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ZNF474, also known as Testis-specific zinc finger protein, is a member of the Krüppel C2H2-type zinc-finger protein family, characterized by a 364 amino acid structure that includes a single C2H2-type zinc finger domain. ZNF474 plays a crucial role in transcriptional regulation, particularly in testis development and function, highlighting its importance in reproductive biology. ZNF474 is located on chromosome 5, which is significant as this location is associated with various genetic disorders, including Cockayne syndrome and familial adenomatous polyposis, due to involvement in critical genomic functions. Understanding ZNF474 and its interactions can provide insights into mechanisms of gene regulation and potential implications in developmental and reproductive health.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ZNF474 Antibody (C-8) References:
- Complete sequencing and characterization of 21,243 full-length human cDNAs. | Ota, T., et al. 2004. Nat Genet. 36: 40-5. PMID: 14702039
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). | Gerhard, DS., et al. 2004. Genome Res. 14: 2121-7. PMID: 15489334
- Recent advances in myelodysplastic syndromes. | Shadduck, RK., et al. 2007. Exp Hematol. 35: 137-43. PMID: 17379099
- Translocations and mutations involving the nucleophosmin (NPM1) gene in lymphomas and leukemias. | Falini, B., et al. 2007. Haematologica. 92: 519-32. PMID: 17488663
- Fetal trisomy 5 mosaicism: case report and literature review. | Villa, N., et al. 2007. Am J Med Genet A. 143A: 2343-6. PMID: 17702005
- Chromosome 5q subtelomeric deletion syndrome. | Rauch, A. and Dörr, HG. 2007. Am J Med Genet C Semin Med Genet. 145C: 372-6. PMID: 17910075
- Speech and language development in cri du chat syndrome: a critical review. | Kristoffersen, KE. 2008. Clin Linguist Phon. 22: 443-57. PMID: 18484284
- Mapping of 5q35 chromosomal rearrangements within a genomically unstable region. | Buysse, K., et al. 2008. J Med Genet. 45: 672-8. PMID: 18628311
- Revealing the pathogenesis of the 5q- syndrome. | Valent, P. 2008. Eur J Clin Invest. 38: 539-40. PMID: 18717823
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZNF474 Antibody (C-8) | sc-514917 | 200 µg/ml | $322.00 | |||
ZNF474 Antibody (C-8): m-IgG Fc BP-HRP Bundle | sc-531243 | 200 µg Ab; 10 µg BP | $361.00 | |||
ZNF474 Antibody (C-8): m-IgGκ BP-HRP Bundle | sc-524875 | 200 µg Ab, 40 µg BP | $361.00 | |||
ZNF474 Antibody (C-8): m-IgG2a BP-HRP Bundle | sc-547739 | 200 µg Ab; 10 µg BP | $361.00 | |||
ZNF474 Antibody (C-8) AC | sc-514917 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ZNF474 Antibody (C-8) HRP | sc-514917 HRP | 200 µg/ml | $322.00 | |||
ZNF474 Antibody (C-8) FITC | sc-514917 FITC | 200 µg/ml | $336.00 | |||
ZNF474 Antibody (C-8) PE | sc-514917 PE | 200 µg/ml | $349.00 | |||
ZNF474 Antibody (C-8) Alexa Fluor® 488 | sc-514917 AF488 | 200 µg/ml | $364.00 | |||
ZNF474 Antibody (C-8) Alexa Fluor® 546 | sc-514917 AF546 | 200 µg/ml | $364.00 | |||
ZNF474 Antibody (C-8) Alexa Fluor® 594 | sc-514917 AF594 | 200 µg/ml | $364.00 | |||
ZNF474 Antibody (C-8) Alexa Fluor® 647 | sc-514917 AF647 | 200 µg/ml | $364.00 | |||
ZNF474 Antibody (C-8) Alexa Fluor® 680 | sc-514917 AF680 | 200 µg/ml | $364.00 | |||
ZNF474 Antibody (C-8) Alexa Fluor® 790 | sc-514917 AF790 | 200 µg/ml | $364.00 |