ZNF281 Antibody (G-9): sc-137205
- ZNF281 Antibody (G-9) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 679-895 mapping at the C-terminus of ZNF281 of human origin
- recommended for detection of ZNF281 of mouse, rat and human origin by WB, IP, IF and ELISA
- TransCruz reagent for ChIP application (sc-137205 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for ZNF281 Antibody (G-9) for WB applications. These reagents are now offered in bundles with ZNF281 Antibody (G-9) (see ordering information below).
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ZNF281 Antibody (G-9) is a mouse monoclonal IgG1 antibody that detects ZNF281 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99, or zinc finger DNA-binding protein 99, is a member of the Krüppel C2H2-type zinc finger protein family and is characterized by its four C2H2-type zinc fingers that facilitate its role in gene regulation. ZNF281 is predominantly expressed in the nucleus and is crucial for the transcriptional repression of various genes, including Gastrin and ornithine decarboxylase (ODC), by binding to specific DNA sequences in the enhancer regions of these genes. ZNF281 can become phosphorylated by Atm or ATR in response to DNA damage, thereby influencing activity and stability in cellular stress responses. Anti-ZNF281 antibody (G-9) provides a reliable tool for researchers studying the intricate mechanisms of gene regulation and cellular responses to DNA damage, making this reagent essential for advancing our understanding of these critical biological processes.
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ZNF281 Antibody (G-9) References:
- ZNF281/ZBP-99: a new player in epithelial-mesenchymal transition, stemness, and cancer. | Hahn, S. and Hermeking, H. 2014. J Mol Med (Berl). 92: 571-81. PMID: 24838609
- ZNF281 Regulates Cell Proliferation, Migration and Invasion in Colorectal Cancer through Wnt/β-Catenin Signaling. | Qin, CJ., et al. 2019. Cell Physiol Biochem. 52: 1503-1516. PMID: 31112017
- ZNF281/Zfp281 is a target of miR-1 and counteracts muscle differentiation. | Nicolai, S., et al. 2020. Mol Oncol. 14: 294-308. PMID: 31782884
- LncRNA-ZNF281 Interacts with miR-539 to Promote Hepatocellular Carcinoma Cell Invasion and Migration. | Zhang, Z., et al. 2020. Cancer Biother Radiopharm. 35: 137-142. PMID: 32073896
- ZNF281-miR-543 Feedback Loop Regulates Transforming Growth Factor-β-Induced Breast Cancer Metastasis. | Ji, W., et al. 2020. Mol Ther Nucleic Acids. 21: 98-107. PMID: 32512343
- ZNF281 Promotes Colon Fibroblast Activation in TGFβ1-Induced Gut Fibrosis. | Laudadio, I., et al. 2022. Int J Mol Sci. 23: PMID: 36142169
- Inhibition of the transcription factor ZNF281 by SUFU to suppress tumor cell migration. | Deng, Y., et al. 2023. Cell Death Differ. 30: 702-715. PMID: 36220888
- ZNF281 drives hepatocyte senescence in alcoholic liver disease by reducing HK2-stabilized PINK1/Parkin-mediated mitophagy. | Lu, C., et al. 2023. Cell Prolif. 56: e13378. PMID: 36514923
- ZNF281 inhibits mitochondrial biogenesis to facilitate metastasis of hepatocellular carcinoma. | Zhao, Q., et al. 2023. Cell Death Discov. 9: 396. PMID: 37880213
- Expression of ZNF281 in colorectal cancer correlates with response to radiotherapy and survival. | Qin, C., et al. 2023. Ann Med. 55: 2278619. PMID: 37939252
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZNF281 Antibody (G-9) | sc-137205 | 200 µg/ml | $322.00 | |||
ZNF281 Antibody (G-9): m-IgG Fc BP-HRP Bundle | sc-539958 | 200 µg Ab; 10 µg BP | $361.00 | |||
ZNF281 Antibody (G-9): m-IgG1 BP-HRP Bundle | sc-541814 | 200 µg Ab; 20 µg BP | $361.00 | |||
ZNF281 Antibody (G-9) X | sc-137205 X | 200 µg/0.1 ml | $322.00 |