ZEB1 Antibody (H-3): sc-515797
- ZEB1 Antibody (H-3) is a mouse monoclonal IgG2a κ ZEB1 antibody, cited in 46 publications, provided at 200 µg/ml
- raised against amino acids 39-140 of ZEB1 of human origin
- ZEB1 Antibody (H-3) is recommended for detection of ZEB1 of human origin by WB, IP, IF and ELISA
- Anti-ZEB1 Antibody (H-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- TransCruz reagent for Gel Supershift and ChIP applications (sc-515797 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ZEB1 Antibody (H-3) for WB applications. These reagents are now offered in bundles with ZEB1 Antibody (H-3) (see ordering information below).
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SEE ALSO...
ZEB1 Antibody (H-3) is a mouse monoclonal IgG2a kappa light chain antibody designed to detect human ZEB1 with exceptional sensitivity and reliability across multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-ZEB1 antibody (H-3) is raised against amino acids 39-140 of human ZEB1, ensuring precise targeting and strong reactivity in experiments involving human samples. ZEB1, also known as AREB6, BZP, DELTAEF1, FECD6, NIL2A, PPCD3, TCF8, ZFHEP, and ZFHX1A, is a pivotal non-receptor transcription factor that plays a crucial role in regulating gene expression during embryonic development, particularly within mesodermal tissues, and in the maturation of various tissues. Structurally, ZEB1 contains two zinc finger domains essential for DNA binding and transcriptional repression, a homeodomain involved in protein-protein interactions, and three repression domains that facilitate modulating gene expression through mechanisms such as site competition and enhancer silencing. ZEB1 interacts with several key proteins, including C-terminal binding proteins (CtBP) which serve as corepressors, and SMAD proteins that are integral to TGF-β signaling pathways, thereby influencing processes like epithelial-mesenchymal transition (EMT) and cellular differentiation. ZEB1′s interaction with the TSHβ gene T3-response element underscores a role in the regulation of gene-specific responses to thyroid hormones, which are vital for metabolic and developmental functions. Beyond foundational roles in embryogenesis and tissue development, ZEB1 is also implicated in the regulation of skeletal structure formation and has been associated with various physiological and pathological conditions, including cancer progression and fibrosis. ZEB1 monoclonal antibody (H-3) is available in both non-conjugated and multiple conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ZEB1 Antibody (H-3) | sc-515797 | 200 µg/ml | $322.00 | |||
ZEB1 Antibody (H-3): m-IgG Fc BP-HRP Bundle | sc-531517 | 200 µg Ab; 10 µg BP | $361.00 | |||
ZEB1 Antibody (H-3): m-IgGκ BP-HRP Bundle | sc-525222 | 200 µg Ab, 40 µg BP | $361.00 | |||
ZEB1 Antibody (H-3): m-IgG2a BP-HRP Bundle | sc-547808 | 200 µg Ab; 10 µg BP | $361.00 | |||
ZEB1 Antibody (H-3) X | sc-515797 X | 200 µg/0.1 ml | $322.00 | |||
ZEB1 Antibody (H-3) AC | sc-515797 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ZEB1 Antibody (H-3) HRP | sc-515797 HRP | 200 µg/ml | $322.00 | |||
ZEB1 Antibody (H-3) FITC | sc-515797 FITC | 200 µg/ml | $336.00 | |||
ZEB1 Antibody (H-3) PE | sc-515797 PE | 200 µg/ml | $349.00 | |||
ZEB1 Antibody (H-3) Alexa Fluor® 488 | sc-515797 AF488 | 200 µg/ml | $364.00 | |||
ZEB1 Antibody (H-3) Alexa Fluor® 546 | sc-515797 AF546 | 200 µg/ml | $364.00 | |||
ZEB1 Antibody (H-3) Alexa Fluor® 594 | sc-515797 AF594 | 200 µg/ml | $364.00 | |||
ZEB1 Antibody (H-3) Alexa Fluor® 647 | sc-515797 AF647 | 200 µg/ml | $364.00 | |||
ZEB1 Antibody (H-3) Alexa Fluor® 680 | sc-515797 AF680 | 200 µg/ml | $364.00 | |||
ZEB1 Antibody (H-3) Alexa Fluor® 790 | sc-515797 AF790 | 200 µg/ml | $364.00 |