X11β Antibody (H-7): sc-376499
- X11β Antibody (H-7) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 3-31 at the N-terminus of X11β of human origin
- recommended for detection of X11β of human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for X11β Antibody (H-7) for WB applications. These reagents are now offered in bundles with X11β Antibody (H-7) (see ordering information below).
X11β Antibody (H-7) is a mouse monoclonal IgG1 antibody that detects X11β in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). X11β, also known as Mint 2, plays a crucial role in the regulation of β-Amyloid precursor protein (β-APP) processing, which is significant in the context of Alzheimer′s disease. X11β is primarily located in the cytoplasm and interacts with β-APP via phosphotyrosine binding (PTB) domain, effectively modulating β-APP secretion and influencing internalization through the YENPTY motif. X11β interaction with β-APP helps maintain cellular homeostasis by slowing down processing pathways that lead to amyloid plaque formation, a hallmark of Alzheimer′s pathology. X11β has multiple splice variants, including X11α and X11γ, which further diversify functional roles in neuronal signaling and protein interactions. Anti-X11β antibody (H-7) serves as an essential tool for researchers investigating molecular mechanisms underlying Alzheimer′s disease and protein interactions contributing to neurodegeneration.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
X11β Antibody (H-7) | sc-376499 | 200 µg/ml | $322.00 | |||
X11β Antibody (H-7): m-IgG Fc BP-HRP Bundle | sc-540585 | 200 µg Ab; 10 µg BP | $361.00 | |||
X11β Antibody (H-7): m-IgG1 BP-HRP Bundle | sc-542223 | 200 µg Ab; 20 µg BP | $361.00 | |||
X11β (H-7) Neutralizing Peptide | sc-376499 P | 100 µg/0.5 ml | $69.00 |