WHIP Antibody (A-8): sc-376438
- WHIP Antibody (A-8) is a mouse monoclonal IgG2b κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1-27 at the N-terminus of WHIP of human origin
- recommended for detection of WHIP of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- TransCruz reagent for ChIP application (sc-376438 X, 200 µg/0.1 ml)
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for WHIP Antibody (A-8) for WB and IHC(P) applications. These reagents are now offered in bundles with WHIP Antibody (A-8) (see ordering information below).
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WHIP Antibody (A-8) is a mouse monoclonal IgG2b antibody that detects WHIP (Werner helicase-interacting protein 1) in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). WHIP plays a crucial role in the regulation of DNA synthesis, particularly in the nucleus, where WHIP is localized in granular structures. WHIP is essential for modulating the initiation events during DNA polymerase-mediated DNA synthesis and possesses ATPase activity that enables WHIP to detect DNA damage or stalled replication forks. The interaction between WHIP and the N-terminal domain of WRN, the protein product of the gene associated with Werner′s syndrome, highlights WHIP′s significance in cellular aging and the potential development of age-related diseases. WHIP is produced in four isoforms due to alternative splicing, which may contribute to WHIP′s functional diversity and regulatory mechanisms in DNA repair processes. Anti-WHIP antibody (A-8) is an invaluable tool for researchers studying the molecular pathways of aging and cancer, providing insights into the intricate relationship between DNA repair and cellular longevity.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
WHIP Antibody (A-8) | sc-376438 | 200 µg/ml | $322.00 | |||
WHIP Antibody (A-8): m-IgG Fc BP-HRP Bundle | sc-537987 | 200 µg Ab; 10 µg BP | $361.00 | |||
WHIP Antibody (A-8): m-IgGκ BP-HRP Bundle | sc-535490 | 200 µg Ab; 40 µg BP | $361.00 | |||
WHIP Antibody (A-8): m-IgG2b BP-HRP Bundle | sc-549909 | 200 µg Ab; 10 µg BP | $361.00 | |||
WHIP (A-8) Neutralizing Peptide | sc-376438 P | 100 µg/0.5 ml | $69.00 | |||
WHIP Antibody (A-8) X | sc-376438 X | 200 µg/0.1 ml | $322.00 |