WDR70 Antibody (C-5): sc-398268
- WDR70 Antibody (C-5) is a mouse monoclonal IgG2a κ WDR70 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 355-654 mapping at the C-terminus of WDR70 of human origin
- WDR70 Antibody (C-5) is recommended for detection of WDR70 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-WDR70 Antibody (C-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for WDR70 Antibody (C-5) for WB applications. These reagents are now offered in bundles with WDR70 Antibody (C-5) (see ordering information below).
WDR70 Antibody (C-5) is a mouse monoclonal IgG2a kappa light chain antibody that detects WDR70 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-WDR70 antibody (C-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. WDR70, which consists of 654 amino acids and features seven WD repeats, plays a crucial role in cellular processes by participating in the assembly of protein complexes, which is essential for regulating signal transduction, apoptosis, transcriptional regulation, and cell cycle control. The presence of WD repeats, characterized by a conserved core of 40-60 amino acids that typically form a tertiary propeller structure, allows WDR70 to interact with various proteins, facilitating complex formation that is vital for maintaining cellular homeostasis and responding to environmental signals. Encoded by a gene located on human chromosome 5q13.3, WDR70 is part of the WD repeat GAD-1 family, underscoring its importance in a wide array of biological functions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
WDR70 Antibody (C-5) References:
- The WD repeat: a common architecture for diverse functions. | Smith, TF., et al. 1999. Trends Biochem Sci. 24: 181-5. PMID: 10322433
- Thirty-plus functional families from a single motif. | Yu, L., et al. 2000. Protein Sci. 9: 2470-6. PMID: 11206068
- WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseases. | Li, D. and Roberts, R. 2001. Cell Mol Life Sci. 58: 2085-97. PMID: 11814058
- The WD-repeat protein superfamily in Arabidopsis: conservation and divergence in structure and function. | van Nocker, S. and Ludwig, P. 2003. BMC Genomics. 4: 50. PMID: 14672542
- Phylogenetic, structural and functional relationships between WD- and Kelch-repeat proteins. | Hudson, AM. and Cooley, L. 2008. Subcell Biochem. 48: 6-19. PMID: 18925367
- The ancient regulatory-protein family of WD-repeat proteins. | Neer, EJ., et al. 1994. Nature. 371: 297-300. PMID: 8090199
- Folding of proteins with WD-repeats: comparison of six members of the WD-repeat superfamily to the G protein beta subunit. | Garcia-Higuera, I., et al. 1996. Biochemistry. 35: 13985-94. PMID: 8909296
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
WDR70 Antibody (C-5) | sc-398268 | 200 µg/ml | $322.00 | |||
WDR70 Antibody (C-5): m-IgG Fc BP-HRP Bundle | sc-530727 | 200 µg Ab; 10 µg BP | $361.00 | |||
WDR70 Antibody (C-5): m-IgGκ BP-HRP Bundle | sc-524261 | 200 µg Ab, 40 µg BP | $361.00 | |||
WDR70 Antibody (C-5): m-IgG2a BP-HRP Bundle | sc-547573 | 200 µg Ab; 10 µg BP | $361.00 | |||
WDR70 Antibody (C-5) AC | sc-398268 AC | 500 µg/ml, 25% agarose | $424.00 | |||
WDR70 Antibody (C-5) HRP | sc-398268 HRP | 200 µg/ml | $322.00 | |||
WDR70 Antibody (C-5) FITC | sc-398268 FITC | 200 µg/ml | $336.00 | |||
WDR70 Antibody (C-5) PE | sc-398268 PE | 200 µg/ml | $349.00 | |||
WDR70 Antibody (C-5) Alexa Fluor® 488 | sc-398268 AF488 | 200 µg/ml | $364.00 | |||
WDR70 Antibody (C-5) Alexa Fluor® 546 | sc-398268 AF546 | 200 µg/ml | $364.00 | |||
WDR70 Antibody (C-5) Alexa Fluor® 594 | sc-398268 AF594 | 200 µg/ml | $364.00 | |||
WDR70 Antibody (C-5) Alexa Fluor® 647 | sc-398268 AF647 | 200 µg/ml | $364.00 | |||
WDR70 Antibody (C-5) Alexa Fluor® 680 | sc-398268 AF680 | 200 µg/ml | $364.00 | |||
WDR70 Antibody (C-5) Alexa Fluor® 790 | sc-398268 AF790 | 200 µg/ml | $364.00 |